PDB entry 7bts

View 7bts on RCSB PDB site
Description: Structure of human beta1 adrenergic receptor bound to epinephrine and nanobody 6B9
Class: membrane protein
Keywords: G protein coupled receptor, membrane protein
Deposited on 2020-04-02, released 2020-12-02
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-05-12, with a file datestamp of 2021-05-07.
Experiment type: XRAY
Resolution: 3.13 Å
R-factor: N/A
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Lysozyme-Beta-1 adrenergic receptor chimera
    Species: Homo sapiens [TaxId:9606]
    Gene: ADRB1, ADRB1R, B1AR
    Database cross-references and differences (RAF-indexed):
    • Uniprot D9IEF7 (8-167)
      • expression tag (0-7)
      • engineered mutation (60)
      • engineered mutation (103)
      • linker (168-169)
    • PDB 7BTS (170-End)
  • Chain 'B':
    Compound: Camelid Antibody Fragment
    Species: VICUGNA PACOS [TaxId:30538]
    Database cross-references and differences (RAF-indexed):
    • PDB 7BTS (0-119)
    Domains in SCOPe 2.08: d7btsb1, d7btsb2
  • Heterogens: ALE, SO4, NA, EPE, CLR, 1WV

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >7btsB (B:)
    qvqlqesggglvqaggslrlscaasgsifalnimgwyrqapgkqrelvaaihsggttnya
    nsvkgrftisrdnaantvylqmnslkpedtavyycnvkdfgaiiydydywgqgtqvtvss