PDB entry 7azb

View 7azb on RCSB PDB site
Description: Structure of DDR2 DS domain in complex with VHH
Class: membrane protein
Keywords: Kinase, Extracellular domain, Receptor Tyrosine kinase Discoidin domain-containing receptor 2, collagen, signal transduction, cell communication, MEMBRANE PROTEIN
Deposited on 2020-11-16, released 2020-11-25
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-11-25, with a file datestamp of 2020-11-20.
Experiment type: XRAY
Resolution: 2.62 Å
R-factor: N/A
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Discoidin domain-containing receptor 2
    Species: Homo sapiens [TaxId:9606]
    Gene: DDR2, NTRKR3, TKT, TYRO10
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7azba_
  • Chain 'B':
    Compound: vhh
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7AZB
    Domains in SCOPe 2.08: d7azbb_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >7azbA (A:)
alanpaicryplgmsggqipdeditassqwsestaakygrldseegdgawcpeipvepdd
lkeflqidlhtlhfitlvgtqgrhagghgiefapmykinysrdgtrwiswrnrhgkqvld
gnsnpydiflkdleppivarfvrfipvtdhsmnvcmrvelygcvwldg

    Sequence, based on observed residues (ATOM records): (download) 
    >7azbA (A:)
aicryplgmsggqipdeditassqwsestaakygrldseegdgawcpeipvepddlkefl
qidlhtlhfitlvgtqgrhagghgiefapmykinysrdgtrwiswrnrhgkqvldgnsnp
ydiflkdleppivarfvrfipvtdhsmnvcmrvelygcvw

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >7azbB (B:)
mkyllptaaagllllaaqpamaevqlqasgggfvqpggslrlscaasgssswldgmgwfr
qapgkerefvsaisgqdnyasyyadsvkgrftisrdnskntvylqmnslraedtatyyca
pqrsiyqshkpiywgqgtqvtvssaaahhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >7azbB (B:)
qlqasgggfvqpggslrlscaaldgmgwfrqapgkerefvsaisgnyasyyadsvkgrft
isrdnskntvylqmnslraedtatyycapqrsiyqshkpiywgqgtqvtvss