PDB entry 6zfd

View 6zfd on RCSB PDB site
Description: 14-3-3 zeta bound to the phosphorylated 18E6 C-terminus
Class: protein binding
Keywords: HPV, E6 oncoprotein, 14-3-3, PROTEIN BINDING
Deposited on 2020-06-17, released 2021-02-17
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-02-17, with a file datestamp of 2021-02-12.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 14-3-3 protein zeta/delta,Protein E6
    Species: Human papillomavirus type 18 [TaxId:333761]
    Gene: E6
    Database cross-references and differences (RAF-indexed):
    • Uniprot P63104 (3-231)
      • expression tag (2)
      • conflict (60)
      • conflict (75-77)
      • conflict (159-161)
      • linker (232-235)
    • Uniprot P06463 (236-242)
    Domains in SCOPe 2.08: d6zfda1, d6zfda2
  • Chain 'B':
    Compound: 14-3-3 protein zeta/delta,Protein E6
    Species: Human papillomavirus type 18 [TaxId:333761]
    Gene: E6
    Database cross-references and differences (RAF-indexed):
    • Uniprot P63104 (3-231)
      • conflict (60)
      • conflict (75-77)
      • conflict (159-161)
      • linker (232-235)
    • Uniprot P06463 (236-242)
    Domains in SCOPe 2.08: d6zfdb_
  • Heterogens: TPO, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6zfdA (A:)
gphmdknelvqkaklaeqaeryddmaacmksvteqgaelsneernllsvayknvvgarrs
awrvvssieqktegaaaaqqmareyrekietelrdicndvlsllekflipnasqaeskvf
ylkmkgdyyrylaevaagddkkgivdqsqqayqeafeisaaamqpthpirlglalnfsvf
yyeilnspekacslaktafdeaiaeldtlseesykdstlimqllrdnltlwtggggrrre
tqv

    Sequence, based on observed residues (ATOM records): (download) 
    >6zfdA (A:)
hmdknelvqkaklaeqaeryddmaacmksvteqgaelsneernllsvayknvvgarrsaw
rvvssieqktegaaaaqqmareyrekietelrdicndvlsllekflipnasqaeskvfyl
kmkgdyyrylaevaagddkkgivdqsqqayqeafeisaaamqpthpirlglalnfsvfyy
eilnspekacslaktafdeaiaeldtlseesykdstlimqllrdnltlwtggggrrretq
v

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6zfdB (B:)
gphmdknelvqkaklaeqaeryddmaacmksvteqgaelsneernllsvayknvvgarrs
awrvvssieqktegaaaaqqmareyrekietelrdicndvlsllekflipnasqaeskvf
ylkmkgdyyrylaevaagddkkgivdqsqqayqeafeisaaamqpthpirlglalnfsvf
yyeilnspekacslaktafdeaiaeldtlseesykdstlimqllrdnltlwtggggrrre
tqv

    Sequence, based on observed residues (ATOM records): (download) 
    >6zfdB (B:)
mdknelvqkaklaeqaeryddmaacmksvteqgaelsneernllsvayknvvgarrsawr
vvssieqktegaaaaqqmareyrekietelrdicndvlsllekflipnasqaeskvfylk
mkgdyyrylaevaagddkkgivdqsqqayqeafeisaaamqpthpirlglalnfsvfyye
ilnspekacslaktafdeaiaeldtlseesykdstlimqllrdnltlwtggggrrretqv