PDB entry 6xcb

View 6xcb on RCSB PDB site
Description: Structure of the C. botulinum neurotoxin serotype A light chain protease in complex with covalent inhibitor 20
Class: toxin/inhibitor
Keywords: covalent inhibitor, hydroxamate, TOXIN, TOXIN-INHIBITOR complex
Deposited on 2020-06-08, released 2020-09-23
The last revision prior to the SCOPe 2.07 freeze date was dated 2020-10-21, with a file datestamp of 2020-10-16.
Experiment type: XRAY
Resolution: 1.74 Å
R-factor: N/A
AEROSPACI score: 0.47 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Botulinum neurotoxin type A
    Species: Clostridium botulinum [TaxId:1491]
    Gene: botA, atx, bonT
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0DPI0 (18-End)
      • expression tag (17)
    Domains in SCOPe 2.07: d6xcba1, d6xcba2
  • Heterogens: UZY, ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6xcbA (A:)
hhhhhhssglvprgshmqfvnkqfnykdpvngvdiayikipnvgqmqpvkafkihnkiwv
iperdtftnpeegdlnpppeakqvpvsyydstylstdnekdnylkgvtklferiystdlg
rmlltsivrgipfwggstidtelkvidtncinviqpdgsyrseelnlviigpsadiiqfe
cksfghevlnltrngygstqyirfspdftfgfeeslevdtnpllgagkfatdpavtlahe
lihaghrlygiainpnrvfkvntnayyemsglevsfeelrtfgghdakfidslqenefrl
yyynkfkdiastlnkaksivgttaslqymknvfkekyllsedtsgkfsvdklkfdklykm
lteiytednfvkffkvlnrktylnfdkavfkinivpkvnytiydgfnlrntnlaanfngq
nteinnmnftklknftglfe

    Sequence, based on observed residues (ATOM records): (download) 
    >6xcbA (A:)
qfvnkqfnykdpvngvdiayikipnvqmqpvkafkihnkiwviperdtftnpeegdlnpp
peakqvpvsyydstylstdnekdnylkgvtklferiystdlgrmlltsivrgipfwggst
idtelkvidtncinviqsyrseelnlviigpsadiiqfecksfglnltrngygstqyirf
spdftfgfeeslevdtnpllgagkfatdpavtlahelihaghrlygiainpnrvfkvntn
ayyemsglevsfeelrtfgghdakfidslqenefrlyyynkfkdiastlnkaksivgtta
slqymknvfkekyllsedtsgkfsvdklkfdklykmlteiytednfvkffkvlnrktyln
fdkavfkinivpkvnytiydgfnlrntnlaanfngqnteinnmnftklknftgl