PDB entry 6x9s

View 6x9s on RCSB PDB site
Description: HIV-1 Envelope Glycoprotein BG505 SOSIP.664 expressed in stable CHO cells in complex with RM20A3 Fab
Class: viral protein/immune system
Keywords: HIV-1, Envelope, glycoprotein, spike, vaccine, VIRAL PROTEIN-IMMUNE SYSTEM complex
Deposited on 2020-06-03, released 2020-11-04
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-11-25, with a file datestamp of 2020-11-20.
Experiment type: EM
Resolution: 3.1 Å
R-factor: N/A
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: HIV-1 Envelope Glycoprotein BG505 SOSIP.664 gp120
    Species: HUMAN IMMUNODEFICIENCY VIRUS 1 [TaxId:11676]
    Gene: ENV
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q2N0S6
      • engineered mutation (335)
      • engineered mutation (503)
  • Chain 'B':
    Compound: HIV-1 Envelope Glycoprotein BG505 SOSIP.664 gp41
    Species: HUMAN IMMUNODEFICIENCY VIRUS 1 [TaxId:11676]
    Gene: ENV
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q2N0S6
      • engineered mutation (93)
  • Chain 'H':
    Compound: RM20A3 Fab Heavy Chain
    Species: Macaca mulatta [TaxId:9544]
    Database cross-references and differences (RAF-indexed):
    • PDB 6X9S (0-End)
    Domains in SCOPe 2.08: d6x9sh_
  • Chain 'L':
    Compound: RM20A3 Fab Light Chain
    Species: Macaca mulatta [TaxId:9544]
    Database cross-references and differences (RAF-indexed):
    • PDB 6X9S (0-End)
  • Heterogens: NAG

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    No sequence available.

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >6x9sH (H:)
evqlvetggglvqpggslklscrasgytfssfamswvrqapgkglewvslindrggltfy
vdsvkgrftisrdnskntlslqmhslrdgdtavyycatggmssalqsskyyfdfwgqgal
vtvss

    Sequence, based on observed residues (ATOM records): (download) 
    >6x9sH (H:)
evqlvetggglvqpggslklscrasgytfssfamswvrqapgkglewvslindrggltfy
vdsvkgrftisrdnskntlslqmhslrdgdtavyycatggmssalqsskyyfdfwgqgal
vtvs

  • Chain 'L':
    No sequence available.