PDB entry 6urh

View 6urh on RCSB PDB site
Description: Crystal structure of broadly neutralizing antibody AR3X in complex with Hepatitis C virus envelope glycoprotein E2 ectodomain
Class: viral protein/immune system
Keywords: HCV glycoprotein, broadly neutralizing antibodies, VIRAL PROTEIN-IMMUNE SYSTEM complex
Deposited on 2019-10-23, released 2020-03-18
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-09.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: N/A
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'C':
    Compound: HCV envelope glycoprotein E2
    Species: Hepacivirus C [TaxId:11103]
    Database cross-references and differences (RAF-indexed):
  • Chain 'H':
    Compound: AR3X Heavy Chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6URH
    Domains in SCOPe 2.08: d6urhh_
  • Chain 'L':
    Compound: AR3X Light Chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6URH (0-End)
    Domains in SCOPe 2.08: d6urhl1, d6urhl2
  • Heterogens: NAG, HOH

PDB Chain Sequences:

  • Chain 'C':
    No sequence available.

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >6urhH (H:)
qvqleqsgaevkkpgssvkvsckasggtfssfvinwvrqapgqglewvggifqapgpere
wlrdinpisgtinyaqrfqgrvtmtadesmttvymelsslrsedtamyycarenkfrycr
ggscysgafdmwgqgtmvtvssastkgpsvfplapsskstsggtaalgclvkdyfpepvt
vswnsgaltsgvhtfpavlqssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkrv
epkscdkthhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >6urhH (H:)
vqleqsgaevkkpgssvkvsckasggtfssfvinwvrqapgqglewvggifqapgperew
lrdinpisgtinyaqrfqgrvtmtadesmttvymelsslrsedtamyycarenkfrycrg
gscysgafdmwgqgtmvtvssastkgpsvfplapsskstsggtaalgclvkdyfpepvtv
swnsgaltsgvhtfpavlqssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkrve
pk

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >6urhL (L:)
eieltqspatlsvspgesatlscrasqsvsdnlawyqqkpgqaprlliygassrapaipg
rfsgsgsgtdftltisrlepedlavyhcqqygaspwtfgqgtkveikrtvaapsvfifpp
sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
lskadyekhkvyacevthqglsspvtksfnrgec

    Sequence, based on observed residues (ATOM records): (download) 
    >6urhL (L:)
eieltqspatlsvspgesatlscrasqsvsdnlawyqqkpgqaprlliygassrapaipg
rfsgsgsgtdftltisrlepedlavyhcqqygaspwtfgqgtkveikrtvaapsvfifpp
sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
lskadyekhkvyacevthqglsspvtksfnrge