PDB entry 6u3n

View 6u3n on RCSB PDB site
Description: LS2.8/3.15 - DQ2-P.fluor-alpha1a complex
Class: immune system
Keywords: Immune Complex, Celiac disease, Gliadin epitope, TCR cross-reactivity, IMMUNE SYSTEM
Deposited on 2019-08-22, released 2019-12-18
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: N/A
AEROSPACI score: 0.22 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: MHC class II HLA-DQ-alpha chain
    Species: Homo sapiens [TaxId:9606]
    Gene: HLA-DQA1
    Database cross-references and differences (RAF-indexed):
    • Uniprot O19705 (Start-182)
      • conflict (46)
    Domains in SCOPe 2.08: d6u3na1, d6u3na2
  • Chain 'B':
    Compound: MHC class II HLA-DQ-beta-1
    Species: Homo sapiens [TaxId:9606]
    Gene: HLA-DQB1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6u3nb1, d6u3nb2
  • Chain 'C':
    Compound: peptide
    Species: Pseudomonas fluorescens [TaxId:294]
    Database cross-references and differences (RAF-indexed):
    • PDB 6U3N (0-End)
  • Chain 'D':
    Compound: T-CELL RECEPTOR, LS2.8/3.15 alpha
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6U3N (0-End)
    Domains in SCOPe 2.08: d6u3nd1, d6u3nd2
  • Chain 'E':
    Compound: T-CELL RECEPTOR, LS2.8/3.15 beta
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6U3N (Start-243)
    Domains in SCOPe 2.08: d6u3ne1, d6u3ne2
  • Heterogens: NAG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6u3nA (A:)
edivadhvasygvnlyqsygpsgqythefdgdeqfyvdlgrketvwslpvlrqfrfdpqf
altniavlkhnlnslikrsnstaatnevpevtvfskspvtlgqpniliclvdnifppvvn
itwlsnghsvtegvsetsflsksdhsffkisyltllpsaeesydckvehwgldkpllkhw
epetsgddddk

    Sequence, based on observed residues (ATOM records): (download) 
    >6u3nA (A:)
ivadhvasygvnlyqsygpsgqythefdgdeqfyvdlgrketvwslpvlrqfrfdpqfal
tniavlkhnlnslikrsnstaatnevpevtvfskspvtlgqpniliclvdnifppvvnit
wlsnghsvtegvsetsflsksdhsffkisyltllpsaeesydckvehwgldkpllkhwep
e

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6u3nB (B:)
ggsgasrdspedfvyqfkgmcyftngtervrlvsrsiynreeivrfdsdvgefravtllg
lpaaeywnsqkdilerkraavdrvcrhnyqlelrttlqrrveptvtispsrtealnhhnl
lvcsvtdfypaqikvrwfrndqeetagvvstplirngdwtfqilvmlemtpqrgdvytch
vehpslqspitvewraqstggddddk

    Sequence, based on observed residues (ATOM records): (download) 
    >6u3nB (B:)
spedfvyqfkgmcyftngtervrlvsrsiynreeivrfdsdvgefravtllglpaaeywn
sqkdilerkraavdrvcrhnyqlelrttlqrrveptvtispshnllvcsvtdfypaqikv
rwfrndqeetagvvstplirngdwtfqilvmlemtpqrgdvytchvehpslqspitvewr
a

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6u3nD (D:)
qsvtqpdihitvsegaslelrcnysygatpylfwyvqspgqglqlllkyfsgdtlvqgik
gfeaefkrsqssfnlrkpsvhwsdaaeyfcavgagsnyqliwgagtkliikpdiqnpdpa
vyqlrdskssdksvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsavawsnk
sdfacanafnnsiipedtffpspess

    Sequence, based on observed residues (ATOM records): (download) 
    >6u3nD (D:)
qsvtqpdihitvsegaslelrcnysygatpylfwyvqspgqglqlllkyfsgdtlvqgik
gfeaefkrsqssfnlrkpsvhwsdaaeyfcavgagsnyqliwgagtkliikpdiqnpdpa
vyqlrdskssdksvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsavawsnk
sdfacanafnnsiipedtf

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >6u3nE (E:)
hmgvtqspthliktrgqqvtlrcspisghksvswyqqvlgqgpqfifqyyekeergrgnf
pdrfsarqfpnysselnvnalllgdsalylcasslegqgaseqffgpgtrltvledlnkv
fppevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplkeq
palndsryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsaeaw
grad

    Sequence, based on observed residues (ATOM records): (download) 
    >6u3nE (E:)
gvtqspthliktrgqqvtlrcspisghksvswyqqvlgqgpqfifqyyekeergrgnfpd
rfsarqfpnysselnvnalllgdsalylcasslegqgaseqffgpgtrltvledlnkvfp
pevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplkeqpa
lndsryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsaeawgr
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