PDB entry 6txr

View 6txr on RCSB PDB site
Description: Structural insights into cubane-modified aptamer recognition of a malaria biomarker
Class: dna
Keywords: Aptamer, Cubamer, PvLDH, DNA
Deposited on 2020-01-14, released 2020-07-15
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-08-05, with a file datestamp of 2020-07-31.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: N/A
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: l-lactate dehydrogenase
    Species: Plasmodium vivax [TaxId:5855]
    Gene: LDH, ldh, PVC01_120033300, PVP01_1229700, PVT01_120033900
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6txra1, d6txra2
  • Chain 'B':
    Compound: l-lactate dehydrogenase
    Species: Plasmodium vivax [TaxId:5855]
    Gene: LDH, ldh, PVC01_120033300, PVP01_1229700, PVT01_120033900
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6txrb1, d6txrb2
  • Chain 'C':
    Compound: l-lactate dehydrogenase
    Species: Plasmodium vivax [TaxId:5855]
    Gene: LDH, ldh, PVC01_120033300, PVP01_1229700, PVT01_120033900
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6txrc1, d6txrc2
  • Chain 'D':
    Compound: l-lactate dehydrogenase
    Species: Plasmodium vivax [TaxId:5855]
    Gene: LDH, ldh, PVC01_120033300, PVP01_1229700, PVT01_120033900
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6txrd1, d6txrd2
  • Heterogens: O0Q, DG, DU, DA, DC, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6txrA (A:)
mtpkpkivlvgsgmiggvmatlivqknlgdvvmfdvvknmpqgkaldtshsnvmaysnck
vtgsnsyddlkgadvvivtagftkapgksdkewnrddllplnnkimieigghiknlcpna
fiivvtnpvdvmvqllfehsgvpknkiiglggvldtsrlkyyisqklnvcprdvnalivg
ahgnkmvllkryitvggiplqefinnkkitdeevegifdrtvntaleivnllaspyvapa
aaiiemaesylkdikkvlvcstllegqyghsnifggtplviggtgveqvielqlnaeekt
kfdeavaetkrmkali

    Sequence, based on observed residues (ATOM records): (download) 
    >6txrA (A:)
pkpkivlvgsgmiggvmatlivqknlgdvvmfdvvknmpqgkaldtshsnvmaysnckvt
gsnsyddlkgadvvivtagftkanrddllplnnkimieigghiknlcpnafiivvtnpvd
vmvqllfehsgvpknkiiglggvldtsrlkyyisqklnvcprdvnalivgahgnkmvllk
ryitvggiplqefinnkkitdeevegifdrtvntaleivnllaspyvapaaaiiemaesy
lkdikkvlvcstllegqyghsnifggtplviggtgveqvielqlnaeektkfdeavaetk
rmkali

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6txrB (B:)
mtpkpkivlvgsgmiggvmatlivqknlgdvvmfdvvknmpqgkaldtshsnvmaysnck
vtgsnsyddlkgadvvivtagftkapgksdkewnrddllplnnkimieigghiknlcpna
fiivvtnpvdvmvqllfehsgvpknkiiglggvldtsrlkyyisqklnvcprdvnalivg
ahgnkmvllkryitvggiplqefinnkkitdeevegifdrtvntaleivnllaspyvapa
aaiiemaesylkdikkvlvcstllegqyghsnifggtplviggtgveqvielqlnaeekt
kfdeavaetkrmkali

    Sequence, based on observed residues (ATOM records): (download) 
    >6txrB (B:)
pkpkivlvgsgmiggvmatlivqknlgdvvmfdvvknmpqgkaldtshsnvmaysnckvt
gsnsyddlkgadvvivtagftkarddllplnnkimieigghiknlcpnafiivvtnpvdv
mvqllfehsgvpknkiiglggvldtsrlkyyisqklnvcprdvnalivgahgnkmvllkr
yitvggiplqefinnkkitdeevegifdrtvntaleivnllaspyvapaaaiiemaesyl
kdikkvlvcstllegqyghsnifggtplviggtgveqvielqlnaeektkfdeavaetkr
mkali

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6txrC (C:)
mtpkpkivlvgsgmiggvmatlivqknlgdvvmfdvvknmpqgkaldtshsnvmaysnck
vtgsnsyddlkgadvvivtagftkapgksdkewnrddllplnnkimieigghiknlcpna
fiivvtnpvdvmvqllfehsgvpknkiiglggvldtsrlkyyisqklnvcprdvnalivg
ahgnkmvllkryitvggiplqefinnkkitdeevegifdrtvntaleivnllaspyvapa
aaiiemaesylkdikkvlvcstllegqyghsnifggtplviggtgveqvielqlnaeekt
kfdeavaetkrmkali

    Sequence, based on observed residues (ATOM records): (download) 
    >6txrC (C:)
pkpkivlvgsgmiggvmatlivqknlgdvvmfdvvknmpqgkaldtshsnvmaysnckvt
gsnsyddlkgadvvivtagftkarddllplnnkimieigghiknlcpnafiivvtnpvdv
mvqllfehsgvpknkiiglggvldtsrlkyyisqklnvcprdvnalivgahgnkmvllkr
yitvggiplqefinnkkitdeevegifdrtvntaleivnllaspyvapaaaiiemaesyl
kdikkvlvcstllegqyghsnifggtplviggtgveqvielqlnaeektkfdeavaetkr
mkali

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6txrD (D:)
mtpkpkivlvgsgmiggvmatlivqknlgdvvmfdvvknmpqgkaldtshsnvmaysnck
vtgsnsyddlkgadvvivtagftkapgksdkewnrddllplnnkimieigghiknlcpna
fiivvtnpvdvmvqllfehsgvpknkiiglggvldtsrlkyyisqklnvcprdvnalivg
ahgnkmvllkryitvggiplqefinnkkitdeevegifdrtvntaleivnllaspyvapa
aaiiemaesylkdikkvlvcstllegqyghsnifggtplviggtgveqvielqlnaeekt
kfdeavaetkrmkali

    Sequence, based on observed residues (ATOM records): (download) 
    >6txrD (D:)
pkpkivlvgsgmiggvmatlivqknlgdvvmfdvvknmpqgkaldtshsnvmaysnckvt
gsnsyddlkgadvvivtagftkanrddllplnnkimieigghiknlcpnafiivvtnpvd
vmvqllfehsgvpknkiiglggvldtsrlkyyisqklnvcprdvnalivgahgnkmvllk
ryitvggiplqefinnkkitdeevegifdrtvntaleivnllaspyvapaaaiiemaesy
lkdikkvlvcstllegqyghsnifggtplviggtgveqvielqlnaeektkfdeavaetk
rmkali