PDB entry 6tvt

View 6tvt on RCSB PDB site
Description: Crystal structure of the haemagglutinin mutant (Gln226Leu, Del228) from an H10N7 seal influenza virus isolated in Germany in complex with human receptor analogue 6'-SLN
Class: viral protein
Keywords: receptor binding, fusion of virus membrane with host plasma membrane, VIRAL PROTEIN
Deposited on 2020-01-10, released 2020-10-21
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-10-21, with a file datestamp of 2020-10-16.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: N/A
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: hemagglutinin HA1
    Species: Influenza A virus (A/harbour seal/Germany/1/2014(H10N7)) [TaxId:1572188]
    Gene: HA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6tvta1, d6tvta2
  • Chain 'B':
    Compound: hemagglutinin HA2
    Species: Influenza A virus (A/harbour seal/Germany/1/2014(H10N7)) [TaxId:1572188]
    Gene: HA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6tvtb_
  • Chain 'C':
    Compound: hemagglutinin HA1
    Species: Influenza A virus (A/harbour seal/Germany/1/2014(H10N7)) [TaxId:1572188]
    Gene: HA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6tvtc1, d6tvtc2
  • Chain 'D':
    Compound: hemagglutinin HA2
    Species: Influenza A virus (A/harbour seal/Germany/1/2014(H10N7)) [TaxId:1572188]
    Gene: HA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6tvtd_
  • Chain 'E':
    Compound: hemagglutinin HA1
    Species: Influenza A virus (A/harbour seal/Germany/1/2014(H10N7)) [TaxId:1572188]
    Gene: HA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6tvte1, d6tvte2
  • Chain 'F':
    Compound: hemagglutinin HA2
    Species: Influenza A virus (A/harbour seal/Germany/1/2014(H10N7)) [TaxId:1572188]
    Gene: HA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6tvtf_
  • Heterogens: GAL, NAG, SIA, CA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6tvtA (A:)
dpdkiclghhavangtivktltneqeevtnatetvestslnrlcmkgrnhkdlgnchpig
mligtpacdlhltgtwdtlierknaiaycypgatvneealrqkimesggiskintgftyg
ssinsagttkacmrnggnsfyaelkwlvsknkgqnfpqttntyrnadtaehlimwgihhp
sstqekndlygtqslsisvgsstyknnfvpvvgarpqvnglsridfhwtlvqpgdkitfs
hnggliapsrvskligrglgiqseapidnsceskcfwrggsintrlpfqnlsprtvgqcp
kyvnkkslmlatgmrnvpelvqgr

    Sequence, based on observed residues (ATOM records): (download) 
    >6tvtA (A:)
dpdkiclghhavangtivktltneqeevtnatetvestslnrlcmkgrnhkdlgnchpig
mligtpacdlhltgtwdtlierknaiaycypgatvneealrqkimesggiskintgftyg
ssinsagttkacmrnggnsfyaelkwlvsknkgqnfpqttntyrnadtaehlimwgihhp
sstqekndlygtqslsisvgsstyknnfvpvvglsridfhwtlvqpgdkitfshngglia
psrvskligrglgiqseapidnsceskcfwrggsintrlpfqnlsprtvgqcpkyvnkks
lmlatgmrnvpe

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6tvtB (B:)
glfgaiagfiengwegmvdgwygfrhqnaqgtgqaadykstqaaidqitgklnriikktn
tefesiesefseidhqignvinwtkdsitdiwtyqaellvamenqhtidmadsemlnlye
rvrkqlrqnaeedgkgcfeiyhacddscmesirnntydhsqyreeallnrlninpvk

    Sequence, based on observed residues (ATOM records): (download) 
    >6tvtB (B:)
glfgaiagfiengwegmvdgwygfrhqnaqgtgqaadykstqaaidqitgklnriikktn
tefesiesefseidhqignvinwtkdsitdiwtyqaellvamenqhtidmadsemlnlye
rvrkqlrqnaeedgkgcfeiyhacddscmesirnntydhsqyreeallnrln

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6tvtC (C:)
dpdkiclghhavangtivktltneqeevtnatetvestslnrlcmkgrnhkdlgnchpig
mligtpacdlhltgtwdtlierknaiaycypgatvneealrqkimesggiskintgftyg
ssinsagttkacmrnggnsfyaelkwlvsknkgqnfpqttntyrnadtaehlimwgihhp
sstqekndlygtqslsisvgsstyknnfvpvvgarpqvnglsridfhwtlvqpgdkitfs
hnggliapsrvskligrglgiqseapidnsceskcfwrggsintrlpfqnlsprtvgqcp
kyvnkkslmlatgmrnvpelvqgr

    Sequence, based on observed residues (ATOM records): (download) 
    >6tvtC (C:)
dpdkiclghhavangtivktltneqeevtnatetvestslnrlcmkgrnhkdlgnchpig
mligtpacdlhltgtwdtlierknaiaycypgatvneealrqkimesggiskintgftyg
ssinsagttkacmrnggnsfyaelkwlvsknkgqnfpqttntyrnadtaehlimwgihhp
sstqekndlygtqslsisvgsstyknnfvpvvlsridfhwtlvqpgdkitfshnggliap
srvskligrglgiqseapidnsceskcfwrggsintrlpfqnlsprtvgqcpkyvnkksl
mlatgmrnvpe

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6tvtD (D:)
glfgaiagfiengwegmvdgwygfrhqnaqgtgqaadykstqaaidqitgklnriikktn
tefesiesefseidhqignvinwtkdsitdiwtyqaellvamenqhtidmadsemlnlye
rvrkqlrqnaeedgkgcfeiyhacddscmesirnntydhsqyreeallnrlninpvk

    Sequence, based on observed residues (ATOM records): (download) 
    >6tvtD (D:)
glfgaiagfiengwegmvdgwygfrhqnaqgtgqaadykstqaaidqitgklnriikktn
tefesiesefseidhqignvinwtkdsitdiwtyqaellvamenqhtidmadsemlnlye
rvrkqlrqnaeedgkgcfeiyhacddscmesirnntydhsqyreeallnrln

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >6tvtE (E:)
dpdkiclghhavangtivktltneqeevtnatetvestslnrlcmkgrnhkdlgnchpig
mligtpacdlhltgtwdtlierknaiaycypgatvneealrqkimesggiskintgftyg
ssinsagttkacmrnggnsfyaelkwlvsknkgqnfpqttntyrnadtaehlimwgihhp
sstqekndlygtqslsisvgsstyknnfvpvvgarpqvnglsridfhwtlvqpgdkitfs
hnggliapsrvskligrglgiqseapidnsceskcfwrggsintrlpfqnlsprtvgqcp
kyvnkkslmlatgmrnvpelvqgr

    Sequence, based on observed residues (ATOM records): (download) 
    >6tvtE (E:)
dpdkiclghhavangtivktltneqeevtnatetvestslnrlcmkgrnhkdlgnchpig
mligtpacdlhltgtwdtlierknaiaycypgatvneealrqkimesggiskintgftyg
ssinsagttkacmrnggnsfyaelkwlvsknkgqnfpqttntyrnadtaehlimwgihhp
sstqekndlygtqslsisvgsstyknnfvpvvgglsridfhwtlvqpgdkitfshnggli
apsrvskligrglgiqseapidnsceskcfwrggsintrlpfqnlsprtvgqcpkyvnkk
slmlatgmrnvpe

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >6tvtF (F:)
glfgaiagfiengwegmvdgwygfrhqnaqgtgqaadykstqaaidqitgklnriikktn
tefesiesefseidhqignvinwtkdsitdiwtyqaellvamenqhtidmadsemlnlye
rvrkqlrqnaeedgkgcfeiyhacddscmesirnntydhsqyreeallnrlninpvk

    Sequence, based on observed residues (ATOM records): (download) 
    >6tvtF (F:)
glfgaiagfiengwegmvdgwygfrhqnaqgtgqaadykstqaaidqitgklnriikktn
tefesiesefseidhqignvinwtkdsitdiwtyqaellvamenqhtidmadsemlnlye
rvrkqlrqnaeedgkgcfeiyhacddscmesirnntydhsqyreeallnrln