PDB entry 6tb2

View 6tb2 on RCSB PDB site
Description: Structure of human haptoglobin-hemoglobin bound to S. aureus IsdH
Class: metal transport
Keywords: Hemoglobin receptor, heme acquisition, inhibitor, METAL TRANSPORT
Deposited on 2019-10-31, released 2019-12-18
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-12-18, with a file datestamp of 2019-12-13.
Experiment type: XRAY
Resolution: 2.9 Å
R-factor: N/A
AEROSPACI score: 0.16 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: Hemoglobin subunit alpha
  Species: Homo sapiens [TaxId:9606]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P69905 (0-140)
  Domains in SCOPe 2.08: d6tb2a_
• Chain 'B':
  Compound: Hemoglobin subunit beta
  Species: Homo sapiens [TaxId:9606]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P68871 (0-145)
  Domains in SCOPe 2.08: d6tb2b_
• Chain 'C':
  Compound: Haptoglobin
  Species: Homo sapiens [TaxId:9606]
  Gene: HP
  Database cross-references and differences (RAF-indexed):
  • Uniprot P00738 (8-266)
    • conflict (44)
    • conflict (67)
    • conflict (71)
    • conflict (101)
• Chain 'D':
  Compound: cell wall surface anchor family protein
  Species: Staphylococcus aureus [TaxId:1280]
  Gene: isdH, EP54_00915, EQ90_06455, HMPREF3211_02292, NCTC10654_01789
  Database cross-references and differences (RAF-indexed):
  • Uniprot A0A0E8IWL6 (Start-353)
    • conflict (340)
• Chain 'E':
  Compound: cell wall surface anchor family protein
  Species: Staphylococcus aureus [TaxId:1280]
  Gene: isdH, EP54_00915, EQ90_06455, HMPREF3211_02292, NCTC10654_01789
  Database cross-references and differences (RAF-indexed):
  • Uniprot A0A0E8IWL6 (Start-353)
    • conflict (340)
• Heterogens: HEM

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >6tb2A (A:)
  vlspadktnvkaawgkvgahageygaealermflsfpttktyfphfdlshgsaqvkghgk
  kvadaltnavahvddmpnalsalsdlhahklrvdpvnfkllshcllvtlaahlpaeftpa
  vhasldkflasvstvltskyr
  

  
  
• Chain 'B':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >6tb2B (B:)
  vhltpeeksavtalwgkvnvdevggealgrllvvypwtqrffesfgdlstpdavmgnpkv
  kahgkkvlgafsdglahldnlkgtfatlselhcdklhvdpenfrllgnvlvcvlahhfgk
  eftppvqaayqkvvagvanalahkyh
  

  
  
• Chain 'C':
  No sequence available.
  
  
• Chain 'D':
  No sequence available.
  
  
• Chain 'E':
  No sequence available.