PDB entry 6stf

View 6stf on RCSB PDB site
Description: Human Rab8a phosphorylated at Ser111 in complex with GDP
Class: signaling protein
Keywords: Parkinson Disease, Phosphorylation, Small G-Protein, SF3 Motif, SIGNALING PROTEIN
Deposited on 2019-09-10, released 2020-04-22
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-05-20, with a file datestamp of 2020-05-15.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: N/A
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Ras-related protein Rab-8A
    Species: Homo sapiens [TaxId:9606]
    Gene: Rab8a, Mel, Rab8
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61006 (1-171)
      • initiating methionine (0)
      • expression tag (172-173)
    Domains in SCOPe 2.08: d6stfa1, d6stfa2, d6stfa3
  • Chain 'B':
    Compound: Ras-related protein Rab-8A
    Species: Homo sapiens [TaxId:9606]
    Gene: Rab8a, Mel, Rab8
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61006 (1-171)
      • initiating methionine (0)
      • expression tag (172)
    Domains in SCOPe 2.08: d6stfb1, d6stfb2, d6stfb3
  • Chain 'C':
    Compound: Ras-related protein Rab-8A
    Species: Homo sapiens [TaxId:9606]
    Gene: Rab8a, Mel, Rab8
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6stfc_
  • Chain 'D':
    Compound: Ras-related protein Rab-8A
    Species: Homo sapiens [TaxId:9606]
    Gene: Rab8a, Mel, Rab8
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6stfd_
  • Chain 'E':
    Compound: Ras-related protein Rab-8A
    Species: Homo sapiens [TaxId:9606]
    Gene: Rab8a, Mel, Rab8
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61006 (1-171)
      • expression tag (172)
    Domains in SCOPe 2.08: d6stfe1, d6stfe2
  • Heterogens: SEP, MG, GDP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6stfA (A:)
mdylfkllligdsgvgktcvlfrfsedafnstfistigidfkirtieldgkriklqiwdt
agqerfrtittayyrgamgimlvyditneksfdnirnwirnieehasadvekmilgnkcd
vndkrqvskergeklaldygikfmetsakaninvenafftlardikakmdkkhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >6stfA (A:)
mdylfkllligdsgvgktcvlfrfsedafnstfistigidfkirtieldgkriklqiwdt
agqerfrtittayyrgamgimlvyditneksfdnirnwirnieehasadvekmilgnkcd
vndkrqvskergeklaldygikfmetsakaninvenafftlardikakmdkkhh

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6stfB (B:)
mdylfkllligdsgvgktcvlfrfsedafnstfistigidfkirtieldgkriklqiwdt
agqerfrtittayyrgamgimlvyditneksfdnirnwirnieehasadvekmilgnkcd
vndkrqvskergeklaldygikfmetsakaninvenafftlardikakmdkkhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >6stfB (B:)
mdylfkllligdsgvgktcvlfrfsedafnstfistigidfkirtieldgkriklqiwdt
atittayyrgamgimlvyditneksfdnirnwirnieehasadvekmilgnkcdvndkrq
vskergeklaldygikfmetsakaninvenafftlardikakmdkkh

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6stfC (C:)
mdylfkllligdsgvgktcvlfrfsedafnstfistigidfkirtieldgkriklqiwdt
agqerfrtittayyrgamgimlvyditneksfdnirnwirnieehasadvekmilgnkcd
vndkrqvskergeklaldygikfmetsakaninvenafftlardikakmdkkhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >6stfC (C:)
dylfkllligdsgvgktcvlfrfsedafnstfisidfkirtieldgkriklqiwdtagqe
rtittayyrgamgimlvyditneksfdnirnwirnieehasadvekmilgnkcdvndkrq
vskergeklaldygikfmetsakaninvenafftlardikakmdkk

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6stfD (D:)
mdylfkllligdsgvgktcvlfrfsedafnstfistigidfkirtieldgkriklqiwdt
agqerfrtittayyrgamgimlvyditneksfdnirnwirnieehasadvekmilgnkcd
vndkrqvskergeklaldygikfmetsakaninvenafftlardikakmdkkhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >6stfD (D:)
ylfkllligdsgvgktcvlfrfsedafnstfistigidfkirtieldgkriklqiwdtay
yrgamgimlvyditneksfdnirnwirnieehasadvekmilgnkcdvndkrqvskerge
klaldygikfmetsakaninvenafftlardikakmdk

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >6stfE (E:)
mdylfkllligdsgvgktcvlfrfsedafnstfistigidfkirtieldgkriklqiwdt
agqerfrtittayyrgamgimlvyditneksfdnirnwirnieehasadvekmilgnkcd
vndkrqvskergeklaldygikfmetsakaninvenafftlardikakmdkkhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >6stfE (E:)
dylfkllligdsgvgktcvlfrfsedafnstfistigidfkirtieldgkriklqiwdty
yrgamgimlvyditneksfdnirnwirnieehasadvekmilgnkcdvndkrqvskerge
klaldygikfmetsakaninvenafftlardikakmdkkh