PDB entry 6rqm

View 6rqm on RCSB PDB site
Description: A blocking anti-CTLA-4 Nanobody (KN044) complexed with CTLA-4
Class: immune system
Keywords: Antibody, check-point, CTLA-4, receptor, IMMUNE SYSTEM
Deposited on 2019-05-16, released 2020-07-08
The last revision prior to the SCOPe 2.07 freeze date was dated 2020-07-08, with a file datestamp of 2020-07-03.
Experiment type: XRAY
Resolution: 3 Å
R-factor: N/A
AEROSPACI score: 0.13 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: cytotoxic t-lymphocyte protein 4
    Species: Homo sapiens [TaxId:9606]
    Gene: CTLA4, CD152
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6rqma_
  • Chain 'B':
    Compound: A blocking anti-CTLA-4 nanobody (KN044)
    Species: Camelus bactrianus [TaxId:9837]
    Database cross-references and differences (RAF-indexed):
    • PDB 6RQM (0-End)
    Domains in SCOPe 2.07: d6rqmb_

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6rqmA (A:)
amhvaqpavvlassrgiasfvceyaspgkatevrvtvlrqadsqvtevcaatymmgnelt
flddsictgtssgnqvnltiqglramdtglyickvelmypppyylgigngtqiyvidpep
cpdsd

    Sequence, based on observed residues (ATOM records): (download) 
    >6rqmA (A:)
hvaqpavvlaasfvceyaspgkatevrvtvlrqadsqvtevcaatymmgneltflddsic
tgtssgnqvnltiqglramdtglyickvelmypppyylgigngtqiyvidp

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6rqmB (B:)
qvqlvesggglvqpggslrlscaasgyiysaycmgwfrqapgkglegvaaiyigggstyy
adsvkgrftisrdnskntlylqmnslraedtavyycaadviptetclggswsgpfgywgq
gtlvtvssgsmdpggshhhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >6rqmB (B:)
qvqlvesggglvqpggslrlscaasgyiysaycmgwfrqapgkglegvaaiyigggstyy
adsvkgrftisrdnskntlylqmnslraedtavyycaadviptetclggswsgpfgywgq
gtlvtvss