PDB entry 6qn2

View 6qn2 on RCSB PDB site
Description: Three dimensional structure of human carbonic anhydrase IX in complex with benzenesulfonamide
Class: lyase
Keywords: lyase
Deposited on 2019-02-08, released 2020-02-26
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-03-18, with a file datestamp of 2020-03-13.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: N/A
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Carbonic anhydrase 9
    Species: Homo sapiens [TaxId:9606]
    Gene: CA9, G250, MN
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q16790 (Start-256)
      • engineered mutation (39)
    Domains in SCOPe 2.08: d6qn2a_
  • Chain 'B':
    Compound: Carbonic anhydrase 9
    Species: Homo sapiens [TaxId:9606]
    Gene: CA9, G250, MN
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q16790 (Start-256)
      • engineered mutation (39)
    Domains in SCOPe 2.08: d6qn2b_
  • Chain 'C':
    Compound: Carbonic anhydrase 9
    Species: Homo sapiens [TaxId:9606]
    Gene: CA9, G250, MN
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q16790 (Start-256)
      • engineered mutation (39)
    Domains in SCOPe 2.08: d6qn2c_
  • Chain 'D':
    Compound: Carbonic anhydrase 9
    Species: Homo sapiens [TaxId:9606]
    Gene: CA9, G250, MN
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q16790 (Start-256)
      • engineered mutation (39)
    Domains in SCOPe 2.08: d6qn2d_
  • Heterogens: J92, ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6qn2A (A:)
gpdqshwryggdppwprvspacagrfqspvdirpqlaafspalrplellgfqlpplpelr
lrnnghsvqltlppglemalgpgreyralqlhlhwgaagrpgsehtveghrfpaeihvvh
lstafarvdealgrpgglavlaafleegpeensayeqllsrleeiaeegsetqvpgldis
allpsdfsryfqyegslttppcaqgviwtvfnqtvmlsakqlhtlsdtlwgpgdsrlqln
fratqplngrvieasfp

    Sequence, based on observed residues (ATOM records): (download) 
    >6qn2A (A:)
wryggdppwprvspacagrfqspvdirpqlaafspalrplellgfqlpplpelrlrnngh
svqltlppglemalgpgreyralqlhlhwgaagrpgsehtveghrfpaeihvvhlstafa
rvdealgrpgglavlaafleegpeensayeqllsrleeiaeegsetqvpgldisallpsd
fsryfqyegslttppcaqgviwtvfnqtvmlsakqlhtlsdtlwgpgdsrlqlnfratqp
lngrvieasfp

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6qn2B (B:)
gpdqshwryggdppwprvspacagrfqspvdirpqlaafspalrplellgfqlpplpelr
lrnnghsvqltlppglemalgpgreyralqlhlhwgaagrpgsehtveghrfpaeihvvh
lstafarvdealgrpgglavlaafleegpeensayeqllsrleeiaeegsetqvpgldis
allpsdfsryfqyegslttppcaqgviwtvfnqtvmlsakqlhtlsdtlwgpgdsrlqln
fratqplngrvieasfp

    Sequence, based on observed residues (ATOM records): (download) 
    >6qn2B (B:)
wryggdppwprvspacagrfqspvdirpqlaafspalrplellgfqlpplpelrlrnngh
svqltlppglemalgpgreyralqlhlhwgaagrpgsehtveghrfpaeihvvhlstafa
rvdealgrpgglavlaafleegpeensayeqllsrleeiaeegsetqvpgldisallpsd
fsryfqyegslttppcaqgviwtvfnqtvmlsakqlhtlsdtlwgpgdsrlqlnfratqp
lngrvieasfp

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6qn2C (C:)
gpdqshwryggdppwprvspacagrfqspvdirpqlaafspalrplellgfqlpplpelr
lrnnghsvqltlppglemalgpgreyralqlhlhwgaagrpgsehtveghrfpaeihvvh
lstafarvdealgrpgglavlaafleegpeensayeqllsrleeiaeegsetqvpgldis
allpsdfsryfqyegslttppcaqgviwtvfnqtvmlsakqlhtlsdtlwgpgdsrlqln
fratqplngrvieasfp

    Sequence, based on observed residues (ATOM records): (download) 
    >6qn2C (C:)
wryggdppwprvspacagrfqspvdirpqlaafspalrplellgfqlpplpelrlrnngh
svqltlppglemalgpgreyralqlhlhwgaagrpgsehtveghrfpaeihvvhlstafa
rvdealgrpgglavlaafleegpeensayeqllsrleeiaeegsetqvpgldisallpsd
fsryfqyegslttppcaqgviwtvfnqtvmlsakqlhtlsdtlwgpgdsrlqlnfratqp
lngrvieasfp

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6qn2D (D:)
gpdqshwryggdppwprvspacagrfqspvdirpqlaafspalrplellgfqlpplpelr
lrnnghsvqltlppglemalgpgreyralqlhlhwgaagrpgsehtveghrfpaeihvvh
lstafarvdealgrpgglavlaafleegpeensayeqllsrleeiaeegsetqvpgldis
allpsdfsryfqyegslttppcaqgviwtvfnqtvmlsakqlhtlsdtlwgpgdsrlqln
fratqplngrvieasfp

    Sequence, based on observed residues (ATOM records): (download) 
    >6qn2D (D:)
wryggdppwprvspacagrfqspvdirpqlaafspalrplellgfqlpplpelrlrnngh
svqltlppglemalgpgreyralqlhlhwgaagrpgsehtveghrfpaeihvvhlstafa
rvdealgrpgglavlaafleegpeensayeqllsrleeiaeegsetqvpgldisallpsd
fsryfqyegslttppcaqgviwtvfnqtvmlsakqlhtlsdtlwgpgdsrlqlnfratqp
lngrvieasfp