PDB entry 6pvd

View 6pvd on RCSB PDB site
Description: Structure of human MAIT A-F7 TCR in complex with human MR1-NV18.1
Class: immune system
Keywords: immune system, mait, mr1
Deposited on 2019-07-20, released 2020-04-01
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-05-27, with a file datestamp of 2020-05-22.
Experiment type: XRAY
Resolution: 2.14 Å
R-factor: N/A
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Major histocompatibility complex class I-related gene protein
    Species: Homo sapiens [TaxId:9606]
    Gene: MR1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q95460 (1-270)
      • initiating methionine (0)
      • conflict (261)
    Domains in SCOPe 2.08: d6pvda1, d6pvda2, d6pvda3
  • Chain 'B':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M, CDABP0092, HDCMA22P
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61769 (1-End)
      • initiating methionine (0)
    Domains in SCOPe 2.08: d6pvdb1, d6pvdb2
  • Chain 'C':
    Compound: Major histocompatibility complex class I-related gene protein
    Species: Homo sapiens [TaxId:9606]
    Gene: MR1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q95460 (1-270)
      • initiating methionine (0)
      • conflict (261)
    Domains in SCOPe 2.08: d6pvdc1, d6pvdc2, d6pvdc3
  • Chain 'D':
    Compound: Human TCR alpha chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6PVD
    Domains in SCOPe 2.08: d6pvdd1, d6pvdd2
  • Chain 'E':
    Compound: Human TCR beta chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6PVD
    Domains in SCOPe 2.08: d6pvde1, d6pvde2
  • Chain 'F':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M, CDABP0092, HDCMA22P
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61769 (1-99)
      • initiating methionine (0)
    Domains in SCOPe 2.08: d6pvdf1, d6pvdf2
  • Chain 'G':
    Compound: Human TCR alpha chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6PVD
    Domains in SCOPe 2.08: d6pvdg1, d6pvdg2
  • Chain 'H':
    Compound: Human TCR beta chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6PVD
    Domains in SCOPe 2.08: d6pvdh1, d6pvdh2
  • Heterogens: N18, GOL, NA, ACT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6pvdA (A:)
mrthslryfrlgvsdpihgvpefisvgyvdshpittydsvtrqkeprapwmaenlapdhw
erytqllrgwqqmfkvelkrlqrhynhsgshtyqrmigcelledgsttgflqyaydgqdf
lifnkdtlswlavdnvahtikqaweanqhellyqknwleeeciawlkrfleygkdtlqrt
epplvrvnrketfpgvtalfckahgfyppeiymtwmkngeeivqeidygdilpsgdgtyq
awasieldpqssnlyschvehsgvhmvlqvp

    Sequence, based on observed residues (ATOM records): (download) 
    >6pvdA (A:)
mrthslryfrlgvsdpihgvpefisvgyvdshpittydsvtrqkeprapwmaenlapdhw
erytqllrgwqqmfkvelkrlqrhynhsgshtyqrmigcelledgsttgflqyaydgqdf
lifnkdtlswlavdnvahtikqaweanqhellyqknwleeeciawlkrfleygkdtlqrt
epplvrvnrktalfckahgfyppeiymtwmkngeeivqeidygdilpsgdgtyqawasie
ldpqssnlyschvehsgvhmvlqvp

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6pvdB (B:)
miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm

    Sequence, based on observed residues (ATOM records): (download) 
    >6pvdB (B:)
miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdr

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6pvdC (C:)
mrthslryfrlgvsdpihgvpefisvgyvdshpittydsvtrqkeprapwmaenlapdhw
erytqllrgwqqmfkvelkrlqrhynhsgshtyqrmigcelledgsttgflqyaydgqdf
lifnkdtlswlavdnvahtikqaweanqhellyqknwleeeciawlkrfleygkdtlqrt
epplvrvnrketfpgvtalfckahgfyppeiymtwmkngeeivqeidygdilpsgdgtyq
awasieldpqssnlyschvehsgvhmvlqvp

    Sequence, based on observed residues (ATOM records): (download) 
    >6pvdC (C:)
mrthslryfrlgvsdpihgvpefisvgyvdshpittydsvtrqkeprapwmaenlapdhw
erytqllrgwqqmfkvelkrlqrhynhsgshtyqrmigcelledgsttgflqyaydgqdf
lifnkdtlswlavdnvahtikqaweanqhellyqknwleeeciawlkrfleygkdtlqrt
epplvrvnrketfpgvtalfckahgfyppeiymtwmkngeeiqeidygdilpsgdgtyqa
wasieldnlyschvehsgvhmvlqvp

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6pvdD (D:)
mgqnidqptemtategaivqinctyqtsgfnglfwyqqhageaptflsynvldgleekgr
fssflsrskgysylllkelqmkdsasylcavkdsnyqliwgagtkliikpdiqnpdpavy
qlrdskssdksvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsavawsnksd
facanafnnsiipedtffpspess

    Sequence, based on observed residues (ATOM records): (download) 
    >6pvdD (D:)
qnidqptemtategaivqinctyqtsgfnglfwyqqhageaptflsynvldgleekgrfs
sflsrskgysylllkelqmkdsasylcavkdsnyqliwgagtkliikpdiqnpdpavyql
rdsksvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsavawsnkdfacanaf
nnsiipedtffp

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >6pvdE (E:)
mnagvtqtpkfqvlktgqsmtlqcaqdmnhnsmywyrqdpgmglrliyysasegttdkge
vpngynvsrlnkrefslrlesaapsqtsvyfcassvwtgegsgelffgegsrltvledlk
nvfppevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplk
eqpalndsryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsae
awgrad

    Sequence, based on observed residues (ATOM records): (download) 
    >6pvdE (E:)
gvtqtpkfqvlktgqsmtlqcaqdmnhnsmywyrqdpgmglrliyysasegttdkgevpn
gynvsrlnkrefslrlesaapsqtsvyfcassvwtgegsgelffgegsrltvledlknvf
ppevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplkeqp
alndsryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsaeawg
r

  • Chain 'F':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6pvdF (F:)
miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >6pvdG (G:)
mgqnidqptemtategaivqinctyqtsgfnglfwyqqhageaptflsynvldgleekgr
fssflsrskgysylllkelqmkdsasylcavkdsnyqliwgagtkliikpdiqnpdpavy
qlrdskssdksvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsavawsnksd
facanafnnsiipedtffpspess

    Sequence, based on observed residues (ATOM records): (download) 
    >6pvdG (G:)
qnidqptemtategaivqinctyqtsgfnglfwyqqhageaptflsynvldgleekgrfs
sflsrskgysylllkelqmkdsasylcavkdsnyqliwgagtkliikpdiqnpdpavyql
rdskssdksvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsavawsnksdfa
canafnnsiipedtffpspe

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >6pvdH (H:)
mnagvtqtpkfqvlktgqsmtlqcaqdmnhnsmywyrqdpgmglrliyysasegttdkge
vpngynvsrlnkrefslrlesaapsqtsvyfcassvwtgegsgelffgegsrltvledlk
nvfppevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplk
eqpalndsryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsae
awgrad

    Sequence, based on observed residues (ATOM records): (download) 
    >6pvdH (H:)
nagvtqtpkfqvlktgqsmtlqcaqdmnhnsmywyrqdpgmglrliyysasegttdkgev
pngynvsrlnkrefslrlesaapsqtsvyfcassvwtgegsgelffgegsrltvledlkn
vfppevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplke
qpalndsryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsaea
wgra