PDB entry 6p4a

View 6p4a on RCSB PDB site
Description: HyHEL10 Fab complexed with hen egg lysozyme carrying two mutations (HEL2x-rigid): R21Q and R73E
Class: hydrolase/immune system
Keywords: HyHEL10, HEL2x-rigid, antibody-antigen, HyHEL10-HEL2x, HYDROLASE-IMMUNE SYSTEM complex
Deposited on 2019-05-27, released 2020-05-27
The last revision prior to the SCOPe 2.07 freeze date was dated 2020-05-27, with a file datestamp of 2020-05-22.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: N/A
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'C':
    Compound: Lysozyme C
    Species: Gallus gallus [TaxId:9031]
    Gene: LYZ
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00698 (0-128)
      • engineered mutation (20)
      • engineered mutation (72)
    Domains in SCOPe 2.07: d6p4ac_
  • Chain 'H':
    Compound: HyHEL10 Fab heavy chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 6P4A (0-End)
  • Chain 'L':
    Compound: HyHEL10 Fab light chain
    Species: Mus musculus [TaxId:10090]
    Gene: LC
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6p4al1, d6p4al2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6p4aC (C:)
kvfgrcelaaamkrhgldnyqgyslgnwvcaakfesnfntqatnrntdgstdygilqins
rwwcndgrtpgsenlcnipcsallssditasvncakkivsdgngmnawvawrnrckgtdv
qawirgcrl

  • Chain 'H':
    No sequence available.

  • Chain 'L':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6p4aL (L:)
divltqspatlsvtpgnsvslscrasqsignnlhwyqqkshesprllikyasqsisgips
rfsgsgsgtdftlsinsvetedfgmyfcqqsnswpytfgggtkleikradaaptvsifpp
sseqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqdskdstysmsstlt
ltkdeyerhnsytceathktstspivksfnrnec