PDB entry 6o9z

View 6o9z on RCSB PDB site
Description: Electron cryo-microscopy of the eukaryotic translation initiation factor 2B bound to eukaryotic translation initiation factor 2 from Homo sapiens
Class: translation
Keywords: eukaryotic translation initiation factor 2B, eukaryotic translation initiation factor 2, TRANSLATION
Deposited on 2019-03-15, released 2019-05-15
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-12-18, with a file datestamp of 2019-12-13.
Experiment type: EM
Resolution: 3.03 Å
R-factor: N/A
AEROSPACI score: 0.13 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: Translation initiation factor eIF-2B subunit epsilon
  Species: Homo sapiens [TaxId:9606]
  Gene: EIF2B5, EIF2BE
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q13144
• Chain 'B':
  Compound: Translation initiation factor eIF-2B subunit epsilon
  Species: Homo sapiens [TaxId:9606]
  Gene: EIF2B5, EIF2BE
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q13144
• Chain 'C':
  Compound: Translation initiation factor eIF-2B subunit beta
  Species: Homo sapiens [TaxId:9606]
  Gene: EIF2B2, EIF2BB
  Database cross-references and differences (RAF-indexed):
  • Uniprot P49770 (Start-367)
• Chain 'D':
  Compound: Translation initiation factor eIF-2B subunit beta
  Species: Homo sapiens [TaxId:9606]
  Gene: EIF2B2, EIF2BB
  Database cross-references and differences (RAF-indexed):
  • Uniprot P49770 (Start-367)
• Chain 'E':
  Compound: Translation initiation factor eIF-2B subunit delta
  Species: Homo sapiens [TaxId:9606]
  Gene: EIF2B4, EIF2BD
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q9UI10
• Chain 'F':
  Compound: Translation initiation factor eIF-2B subunit delta
  Species: Homo sapiens [TaxId:9606]
  Gene: EIF2B4, EIF2BD
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q9UI10
• Chain 'G':
  Compound: Translation initiation factor eIF-2B subunit alpha
  Species: Homo sapiens [TaxId:9606]
  Gene: EIF2B1, EIF2BA
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q14232 (0-304)
• Chain 'H':
  Compound: Translation initiation factor eIF-2B subunit alpha
  Species: Homo sapiens [TaxId:9606]
  Gene: EIF2B1, EIF2BA
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q14232 (0-304)
• Chain 'I':
  Compound: Translation initiation factor eIF-2B subunit gamma
  Species: Homo sapiens [TaxId:9606]
  Gene: EIF2B3
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q9NR50 (0-End)
• Chain 'J':
  Compound: Translation initiation factor eIF-2B subunit gamma
  Species: Homo sapiens [TaxId:9606]
  Gene: EIF2B3
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q9NR50 (0-End)
• Chain 'L':
  Compound: Eukaryotic translation initiation factor 2 subunit 1
  Species: Homo sapiens [TaxId:9606]
  Gene: EIF2S1, EIF2A
  Database cross-references and differences (RAF-indexed):
  • Uniprot P05198
  Domains in SCOPe 2.08: d6o9zl1, d6o9zl2
• Chain 'M':
  Compound: Eukaryotic translation initiation factor 2 subunit 1
  Species: Homo sapiens [TaxId:9606]
  Gene: EIF2S1, EIF2A
  Database cross-references and differences (RAF-indexed):
  • Uniprot P05198
  Domains in SCOPe 2.08: d6o9zm1, d6o9zm2

PDB Chain Sequences:

• Chain 'A':
  No sequence available.
  
  
• Chain 'B':
  No sequence available.
  
  
• Chain 'C':
  No sequence available.
  
  
• Chain 'D':
  No sequence available.
  
  
• Chain 'E':
  No sequence available.
  
  
• Chain 'F':
  No sequence available.
  
  
• Chain 'G':
  No sequence available.
  
  
• Chain 'H':
  No sequence available.
  
  
• Chain 'I':
  No sequence available.
  
  
• Chain 'J':
  No sequence available.
  
  
• Chain 'L':
  Sequence, based on SEQRES records: (download)
  

  >6o9zL (L:)
  mdykddddkpglscrfyqhkfpevedvvmvnvrsiaemgayvslleynniegmillsels
  rrrirsinklirigrnecvvvirvdkekgyidlskrrvspeeaikcedkftksktvysil
  rhvaevleytkdeqleslfqrtawvfddkykrpgygaydafkhavsdpsildsldlnede
  revlinninrrltpqavkiradievacygyegidavkealraglncstenmpikinliap
  pryvmttttlerteglsvlsqamavikekieekrgvfnvqmepkvvtdtdetelarqmer
  lerenaevdgdddaeemeakaed
  

  
  Sequence, based on observed residues (ATOM records): (download)
  

  >6o9zL (L:)
  crfyqhkfpevedvvmvnvrsiaemgayvslleynniegmillselsrrrirsinkliri
  grnecvvvirvdkekgyidlskrrvspeeaikcedkftksktvysilrhvaevleytkde
  qleslfqrtawvfddkykrpgygaydafkhavsdpsildsldlnederevlinnin
  

  
  
• Chain 'M':
  Sequence, based on SEQRES records: (download)
  

  >6o9zM (M:)
  mdykddddkpglscrfyqhkfpevedvvmvnvrsiaemgayvslleynniegmillsels
  rrrirsinklirigrnecvvvirvdkekgyidlskrrvspeeaikcedkftksktvysil
  rhvaevleytkdeqleslfqrtawvfddkykrpgygaydafkhavsdpsildsldlnede
  revlinninrrltpqavkiradievacygyegidavkealraglncstenmpikinliap
  pryvmttttlerteglsvlsqamavikekieekrgvfnvqmepkvvtdtdetelarqmer
  lerenaevdgdddaeemeakaed
  

  
  Sequence, based on observed residues (ATOM records): (download)
  

  >6o9zM (M:)
  crfyqhkfpevedvvmvnvrsiaemgayvslleynniegmillselsrrrirsinkliri
  grnecvvvirvdkekgyidlskrrvspeeaikcedkftksktvysilrhvaevleytkde
  qleslfqrtawvfddkykrpgygaydafkhavsdpsildsldlnederevlinnin