SCOPe 2.08: Structural Classification of Proteins

PDB entry 6o4k

View 6o4k on RCSB PDB site
Description: Structure of ALDH7A1 mutant E399Q complexed with NAD
Class: oxidoreductase
Keywords: aldehyde dehydrogenase, nad, oxidoreductase, lysine catabolism
Deposited on 2019-02-28, released 2019-11-06
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-05-20, with a file datestamp of 2020-05-15.
Experiment type: XRAY
Resolution: 2.06 Å
R-factor: N/A
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

Chain 'A':
Compound: Alpha-aminoadipic semialdehyde dehydrogenase
Species: Homo sapiens [TaxId:9606]
Gene: ALDH7A1, ATQ1
Database cross-references and differences (RAF-indexed):
- Uniprot P49419 (Start-512)
  - engineered mutation (400)
Domains in SCOPe 2.08: d6o4ka_
Chain 'B':
Compound: Alpha-aminoadipic semialdehyde dehydrogenase
Species: Homo sapiens [TaxId:9606]
Gene: ALDH7A1, ATQ1
Database cross-references and differences (RAF-indexed):
- Uniprot P49419 (Start-512)
  - engineered mutation (400)
Domains in SCOPe 2.08: d6o4kb_
Chain 'C':
Compound: Alpha-aminoadipic semialdehyde dehydrogenase
Species: Homo sapiens [TaxId:9606]
Gene: ALDH7A1, ATQ1
Database cross-references and differences (RAF-indexed):
- Uniprot P49419 (Start-512)
  - engineered mutation (400)
Domains in SCOPe 2.08: d6o4kc_
Chain 'D':
Compound: Alpha-aminoadipic semialdehyde dehydrogenase
Species: Homo sapiens [TaxId:9606]
Gene: ALDH7A1, ATQ1
Database cross-references and differences (RAF-indexed):
- Uniprot P49419 (Start-512)
  - engineered mutation (400)
Domains in SCOPe 2.08: d6o4kd_
Chain 'E':
Compound: Alpha-aminoadipic semialdehyde dehydrogenase
Species: Homo sapiens [TaxId:9606]
Gene: ALDH7A1, ATQ1
Database cross-references and differences (RAF-indexed):
- Uniprot P49419 (Start-512)
  - engineered mutation (400)
Domains in SCOPe 2.08: d6o4ke_
Chain 'F':
Compound: Alpha-aminoadipic semialdehyde dehydrogenase
Species: Homo sapiens [TaxId:9606]
Gene: ALDH7A1, ATQ1
Database cross-references and differences (RAF-indexed):
- Uniprot P49419 (Start-512)
  - engineered mutation (400)
Domains in SCOPe 2.08: d6o4kf_
Chain 'G':
Compound: Alpha-aminoadipic semialdehyde dehydrogenase
Species: Homo sapiens [TaxId:9606]
Gene: ALDH7A1, ATQ1
Database cross-references and differences (RAF-indexed):
- Uniprot P49419
  - engineered mutation (400)
Domains in SCOPe 2.08: d6o4kg_
Chain 'H':
Compound: Alpha-aminoadipic semialdehyde dehydrogenase
Species: Homo sapiens [TaxId:9606]
Gene: ALDH7A1, ATQ1
Database cross-references and differences (RAF-indexed):
- Uniprot P49419 (Start-512)
  - engineered mutation (400)
Domains in SCOPe 2.08: d6o4kh_
Heterogens: EDO, NAD, CL, HOH

PDB Chain Sequences:

Chain 'A':
Sequence, based on SEQRES records: (download)

>6o4kA (A:)
ghmstllinqpqyawlkelglreenegvyngswggrgevittycpannepiarvrqasva
dyeetvkkareawkiwadipapkrgeivrqigdalrekiqvlgslvslemgkilvegvge
vqeyvdicdyavglsrmiggpilpsersghalieqwnpvglvgiitafnfpvavygwnna
iamicgnvclwkgapttslisvavtkiiakvlednklpgaicsltcggadigtamakder
vnllsftgstqvgkqvglmvqerfgrsllelggnnaiiafedadlslvvpsalfaavgta
gqrcttarrlfihesihdevvnrlkkayaqirvgnpwdpnvlygplhtkqavsmflgave
eakkeggtvvyggkvmdrpgnyveptivtglghdasiahtqtfapilyvfkfkneeevfa
wnnevkqglsssiftkdlgrifrwlgpkgsdcgivnvniptsgaeiggafggekhtgggr
esgsdawkqymrrstctinyskdlplaqgikfq