PDB entry 6nd2
View 6nd2 on RCSB PDB site
Description: Staphylococcus aureus Dihydrofolate Reductase complexed with NADPH and 6-ETHYL-5-[(3R)-3-[2-METHOXY-5-(PYRIDIN-4-YL)PHENYL]BUT-1-YN-1-YL]PYRIMIDINE-2,4-DIAMINE (UCP1063)
Class: oxidoreductase
Keywords: DHFR, Propargyl-linked antifolates, antibiotics, antifolates, OXIDOREDUCTASE
Deposited on
2018-12-13, released
2019-09-25
The last revision prior to the SCOPe 2.08 freeze date was dated
2019-12-18, with a file datestamp of
2019-12-13.
Experiment type: XRAY
Resolution: 2.24 Å
R-factor: N/A
AEROSPACI score: 0.25
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'X':
Compound: dihydrofolate reductase
Species: Staphylococcus aureus [TaxId:1280]
Gene: folA
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d6nd2x_ - Heterogens: GOL, G8J, XNP, HOH