PDB entry 6n13

View 6n13 on RCSB PDB site
Description: UbcH7-Ub Complex with R0RBR Parkin and phosphoubiquitin
Class: ligase
Keywords: E3 enzyme, protein degradation, mitochondrial protein, LIGASE
Deposited on 2018-11-08, released 2018-11-28
The last revision prior to the SCOPe 2.07 freeze date was dated 2018-11-28, with a file datestamp of 2018-11-23.
Experiment type: NMR
Resolution: N/A
R-factor: N/A
AEROSPACI score: 0.06 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: phosphoubiquitin
    Species: Homo sapiens [TaxId:9606]
    Gene: UBC
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6n13a_
  • Chain 'B':
    Compound: E3 ubiquitin-protein ligase parkin
    Species: Homo sapiens [TaxId:9606]
    Gene: PRKN, PARK2
    Database cross-references and differences (RAF-indexed):
    • Uniprot O60260 (0-321)
      • engineered mutation (203)
  • Chain 'C':
    Compound: Ubiquitin-conjugating enzyme E2 L3
    Species: Homo sapiens [TaxId:9606]
    Gene: UBE2L3, UBCE7, UBCH7
    Database cross-references and differences (RAF-indexed):
    • Uniprot P68036 (2-155)
      • engineered mutation (18)
      • engineered mutation (87)
      • engineered mutation (138)
    Domains in SCOPe 2.07: d6n13c_
  • Chain 'D':
    Compound: Ubiquitin
    Species: Homo sapiens [TaxId:9606]
    Gene: UBB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6n13d_
  • Heterogens: ZN

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >6n13A (A:)
    mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
    iqkestlhlvlrlrgg
    

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >6n13C (C:)
    ghmaasrrlmkeleeirksgmknfrniqvdeanlltwqglivpdnppydkgafrieinfp
    aeypfkppkitfktkiyhpnidekgqvklpvisaenwkpatktdqviqslialvndpqpe
    hplradlaeeyskdrkkfsknaeeftkkygekrpvd
    

    Sequence, based on observed residues (ATOM records): (download)
    >6n13C (C:)
    maasrrlmkeleeirksgmknfrniqvdeanlltwqglivpdnppydkgafrieinfpae
    ypfkppkitfktkiyhpnidekgqvklpvisaenwkpatktdqviqslialvndpqpehp
    lradlaeeyskdrkkfsknaeeftkkygekrpvd
    

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download)
    >6n13D (D:)
    mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
    iqkestlhlvlrlrgg