PDB entry 6mt0

View 6mt0 on RCSB PDB site
Description: Crystal structure of human Pim-1 kinase in complex with a quinazolinone-pyrrolodihydropyrrolone inhibitor
Class: transferase
Keywords: serine/threonine protein kinase, TRANSFERASE
Deposited on 2018-10-18, released 2019-01-16
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-05-01, with a file datestamp of 2019-04-26.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: N/A
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Serine/threonine-protein kinase pim-1
    Species: Homo sapiens [TaxId:9606]
    Gene: PIM1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6mt0a_
  • Heterogens: JYG, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6mt0A (A:)
mahhhhhhdevdgplesqyqvgpllgsggfgsvysgirvsdnlpvaikhvekdrisdwge
lpngtrvpmevvllkkvssgfsgvirlldwferpdsfvlilerpepvqdlfdfitergal
qeelarsffwqvleavrhchncgvlhrdikdenilidlnrgelklidfgsgallkdtvyt
dfdgtrvysppewiryhryhgrsaavwslgillydmvcgdipfehdeeiirgqvffrqrv
ssecqhlirwclalrpsdrptfeeiqnhpwmqdvllpqetaeihlh

    Sequence, based on observed residues (ATOM records): (download) 
    >6mt0A (A:)
plesqyqvgpllgsggfgsvysgirvsdnlpvaikhvekdrisdwgelpngtrvpmevvl
lkkvssgfsgvirlldwferpdsfvlilerpepvqdlfdfitergalqeelarsffwqvl
eavrhchncgvlhrdikdenilidlnrgelklidfgsgallkdtvytdfdgtrvysppew
iryhryhgrsaavwslgillydmvcgdipfehdeeiirgqvffrqrvssecqhlirwcla
lrpsdrptfeeiqnhpwmqdvllpqetaeihlh