PDB entry 6mh2
View 6mh2 on RCSB PDB site
Description: Structure of Herceptin Fab without antigen
Class: immune system
Keywords: Herceptin, antibody, Fab fragment, IMMUNE SYSTEM
Deposited on
2018-09-17, released
2019-05-29
The last revision prior to the SCOPe 2.07 freeze date was dated
2019-05-29, with a file datestamp of
2019-05-24.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: N/A
AEROSPACI score: 0.16
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Herceptin Fab arm light chain
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- PDB 6MH2 (0-103)
- Uniprot Q7Z3Y4 (104-213)
Domains in SCOPe 2.07: d6mh2a1, d6mh2a2 - Chain 'B':
Compound: Herceptin Fab arm heavy chain
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Chain 'C':
Compound: Herceptin Fab arm light chain
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- PDB 6MH2 (0-103)
- Uniprot Q7Z3Y4 (104-213)
Domains in SCOPe 2.07: d6mh2c1, d6mh2c2 - Chain 'D':
Compound: Herceptin Fab arm heavy chain
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>6mh2A (A:)
diqmtqspsslsasvgdrvtitcrasqdvntavawyqqkpgkapklliysasflysgvps
rfsgsrsgtdftltisslqpedfatyycqqhyttpptfgqgtkveikrtvaapsvfifpp
sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
lskadyekhkvyacevthqglsspvtksfnrgec
- Chain 'B':
No sequence available.
- Chain 'C':
Sequence, based on SEQRES records: (download)
>6mh2C (C:)
diqmtqspsslsasvgdrvtitcrasqdvntavawyqqkpgkapklliysasflysgvps
rfsgsrsgtdftltisslqpedfatyycqqhyttpptfgqgtkveikrtvaapsvfifpp
sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
lskadyekhkvyacevthqglsspvtksfnrgec
Sequence, based on observed residues (ATOM records): (download)
>6mh2C (C:)
diqmtqspsslsasvgdrvtitcrasqdvntavawyqqkpgkapklliysasflysgvps
rfsgsrsgtdftltisslqpedfatyycqqhyttpptfgqgtkveikrtvaapsvfifpp
asvvcllnnfypreakvqwgnsqesvteqdskdstyslsstltlskadyekhkvyacevt
hqglsspvtksfnrgec
- Chain 'D':
No sequence available.