PDB entry 6lah

View 6lah on RCSB PDB site
Description: Crystal structure of rhesus macaque MHC class I molecule Mamu-B*098 complexed with lysophosphatidylcholine
Class: immune system
Keywords: MHC class I protein, complex, lysophospholipid, IMMUNE SYSTEM
Deposited on 2019-11-12, released 2020-04-22
The last revision prior to the SCOPe 2.07 freeze date was dated 2020-04-22, with a file datestamp of 2020-04-17.
Experiment type: XRAY
Resolution: 1.87 Å
R-factor: N/A
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: MHC class I antigen
    Species: Macaca mulatta [TaxId:9544]
    Gene: Mamu-B
    Database cross-references and differences (RAF-indexed):
    • Uniprot A0A1E1GJG5 (0-276)
      • engineered mutation (167)
    Domains in SCOPe 2.07: d6laha1, d6laha2
  • Chain 'B':
    Compound: Beta-2-microglobulin
    Species: Macaca mulatta [TaxId:9544]
    Gene: B2M
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6lahb_
  • Chain 'C':
    Compound: MHC class I antigen
    Species: Macaca mulatta [TaxId:9544]
    Gene: Mamu-B
    Database cross-references and differences (RAF-indexed):
    • Uniprot A0A1E1GJG5 (0-276)
      • engineered mutation (167)
    Domains in SCOPe 2.07: d6lahc1, d6lahc2
  • Chain 'D':
    Compound: Beta-2-microglobulin
    Species: Macaca mulatta [TaxId:9544]
    Gene: B2M
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6lahd_
  • Heterogens: EKG, ZN, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6lahA (A:)
agshsmryfsttvsrpgrgeprfivvgyvddtqfvrfdsdaaspkmeprapwmeqegpey
weeqtrrvkdaaqtfrvslgnlrgyynqseagshtlqtmsgcdlgpdgrllrgyyqqayd
grdyialnedlrswtaadeaaqntqrkweaagvaeqwraylegecleslrrylengketl
qraeppkthvthhpvsdheatlrcwalgfypaeitltwqrdgedqtqdtelvetrpggdg
tfqkwgavvvpsgeeqrytchvqheglpepltlrwep

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6lahB (B:)
aiqrtpkiqvysrhppengkpnflncyvsgfhpsdievdllkngekmgkvehsdlsfskd
wsfyllyyteftpnekdeyacrvnhvtlsgprtvkwdrdm

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6lahC (C:)
agshsmryfsttvsrpgrgeprfivvgyvddtqfvrfdsdaaspkmeprapwmeqegpey
weeqtrrvkdaaqtfrvslgnlrgyynqseagshtlqtmsgcdlgpdgrllrgyyqqayd
grdyialnedlrswtaadeaaqntqrkweaagvaeqwraylegecleslrrylengketl
qraeppkthvthhpvsdheatlrcwalgfypaeitltwqrdgedqtqdtelvetrpggdg
tfqkwgavvvpsgeeqrytchvqheglpepltlrwep

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6lahD (D:)
aiqrtpkiqvysrhppengkpnflncyvsgfhpsdievdllkngekmgkvehsdlsfskd
wsfyllyyteftpnekdeyacrvnhvtlsgprtvkwdrdm