PDB entry 6l8t

View 6l8t on RCSB PDB site
Description: Crystal structure of the Fab fragment of a humanized HBV therapeutic antibody
Class: immune system
Keywords: Antibody, IMMUNE SYSTEM
Deposited on 2019-11-07, released 2020-02-26
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-09-09, with a file datestamp of 2020-09-04.
Experiment type: XRAY
Resolution: 1.77 Å
R-factor: N/A
AEROSPACI score: 0.46 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: antibody heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6L8T (0-219)
    Domains in SCOPe 2.08: d6l8ta_
  • Chain 'B':
    Compound: Antibody Light Chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6L8T (0-218)
    Domains in SCOPe 2.08: d6l8tb1, d6l8tb2
  • Chain 'C':
    Compound: antibody heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6L8T (0-219)
    Domains in SCOPe 2.08: d6l8tc_
  • Chain 'D':
    Compound: Antibody Light Chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6L8T (0-218)
    Domains in SCOPe 2.08: d6l8td1, d6l8td2
  • Chain 'H':
    Compound: antibody heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6L8T (0-219)
    Domains in SCOPe 2.08: d6l8th_
  • Chain 'L':
    Compound: Antibody Light Chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6L8T (0-218)
    Domains in SCOPe 2.08: d6l8tl1, d6l8tl2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6l8tA (A:)
evqlqesgpglvkpsqtlsltcavsgssitygyhwnwirqfpgnklewigyisydgsvly
npslenrvtitrdtsknqfflklssvtaedtakyycasgfdhwgqgttltvssastkgps
vfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglyslss
vvtvpssslgtqtyicnvnhkpsntkvdkkvepkscdkth

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6l8tB (B:)
dvvmtqsplslpvtlgepasiscrssqslvhsygdtylhwylqkpgqspklliykvsnrf
sgvpdrfsgsgsgtdftlkisrvetedlgvyycsqnthvpytfgggtkleikrtvaapsv
fifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstysl
sstltlskadyekhkvyacevthqglsspvtksfnrgec

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6l8tC (C:)
evqlqesgpglvkpsqtlsltcavsgssitygyhwnwirqfpgnklewigyisydgsvly
npslenrvtitrdtsknqfflklssvtaedtakyycasgfdhwgqgttltvssastkgps
vfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglyslss
vvtvpssslgtqtyicnvnhkpsntkvdkkvepkscdkth

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6l8tD (D:)
dvvmtqsplslpvtlgepasiscrssqslvhsygdtylhwylqkpgqspklliykvsnrf
sgvpdrfsgsgsgtdftlkisrvetedlgvyycsqnthvpytfgggtkleikrtvaapsv
fifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstysl
sstltlskadyekhkvyacevthqglsspvtksfnrgec

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6l8tH (H:)
evqlqesgpglvkpsqtlsltcavsgssitygyhwnwirqfpgnklewigyisydgsvly
npslenrvtitrdtsknqfflklssvtaedtakyycasgfdhwgqgttltvssastkgps
vfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglyslss
vvtvpssslgtqtyicnvnhkpsntkvdkkvepkscdkth

  • Chain 'L':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6l8tL (L:)
dvvmtqsplslpvtlgepasiscrssqslvhsygdtylhwylqkpgqspklliykvsnrf
sgvpdrfsgsgsgtdftlkisrvetedlgvyycsqnthvpytfgggtkleikrtvaapsv
fifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstysl
sstltlskadyekhkvyacevthqglsspvtksfnrgec