PDB entry 6kj8

View 6kj8 on RCSB PDB site
Description: E. coli ATCase holoenzyme mutant - G166P (catalytic chain)
Class: transferase
Keywords: aspartate transcarbamoylase holoenzyme, de novo pyrimidine biosynthesis, TRANSFERASE
Deposited on 2019-07-22, released 2020-03-11
The last revision prior to the SCOPe 2.07 freeze date was dated 2020-03-11, with a file datestamp of 2020-03-06.
Experiment type: XRAY
Resolution: 3.01 Å
R-factor: N/A
AEROSPACI score: 0.13 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: Aspartate carbamoyltransferase catalytic subunit
  Species: Escherichia coli K-12 [TaxId:83333]
  Gene: pyrB, b4245, JW4204
  Database cross-references and differences (RAF-indexed):
  • Uniprot P0A786 (0-End)
    • engineered mutation (165)
• Chain 'B':
  Compound: Aspartate carbamoyltransferase regulatory chain
  Species: Escherichia coli K-12 [TaxId:83333]
  Gene: pyrI, b4244, JW4203
  Database cross-references and differences (RAF-indexed):
  • Uniprot P0A7F3 (Start-152)
  Domains in SCOPe 2.07: d6kj8b1, d6kj8b2
• Chain 'C':
  Compound: Aspartate carbamoyltransferase catalytic subunit
  Species: Escherichia coli K-12 [TaxId:83333]
  Gene: pyrB, b4245, JW4204
  Database cross-references and differences (RAF-indexed):
  • Uniprot P0A786 (0-End)
    • engineered mutation (165)
• Chain 'D':
  Compound: Aspartate carbamoyltransferase regulatory chain
  Species: Escherichia coli K-12 [TaxId:83333]
  Gene: pyrI, b4244, JW4203
  Database cross-references and differences (RAF-indexed):
  • Uniprot P0A7F3 (Start-152)
  Domains in SCOPe 2.07: d6kj8d1, d6kj8d2
• Chain 'E':
  Compound: Aspartate carbamoyltransferase catalytic subunit
  Species: Escherichia coli K-12 [TaxId:83333]
  Gene: pyrB, b4245, JW4204
  Database cross-references and differences (RAF-indexed):
  • Uniprot P0A786 (0-309)
    • engineered mutation (165)
• Chain 'F':
  Compound: Aspartate carbamoyltransferase regulatory chain
  Species: Escherichia coli K-12 [TaxId:83333]
  Gene: pyrI, b4244, JW4203
  Database cross-references and differences (RAF-indexed):
  • Uniprot P0A7F3 (Start-152)
  Domains in SCOPe 2.07: d6kj8f1, d6kj8f2
• Heterogens: ZN, HOH

PDB Chain Sequences:

• Chain 'A':
  No sequence available.
  
  
• Chain 'B':
  Sequence, based on SEQRES records: (download)
  

  >6kj8B (B:)
  mthdnklqveaikrgtvidhipaqigfkllslfkltetdqritiglnlpsgemgrkdlik
  ientflsedqvdqlalyapqatvnridnyevvgksrpslperidnvlvcpnsncishaep
  vsssfavrkrandialkckycekefshnvvlan
  

  
  Sequence, based on observed residues (ATOM records): (download)
  

  >6kj8B (B:)
  krgtvidhipaqigfkllslfkltetdqritiglnlrkdlikientflsedqvdqlalya
  pqatvnridnyevvgksrpslperidnvlvcpnsncishaepvsssfavrkrandialkc
  kycekefshnvvlan
  

  
  
• Chain 'C':
  No sequence available.
  
  
• Chain 'D':
  Sequence, based on SEQRES records: (download)
  

  >6kj8D (D:)
  mthdnklqveaikrgtvidhipaqigfkllslfkltetdqritiglnlpsgemgrkdlik
  ientflsedqvdqlalyapqatvnridnyevvgksrpslperidnvlvcpnsncishaep
  vsssfavrkrandialkckycekefshnvvlan
  

  
  Sequence, based on observed residues (ATOM records): (download)
  

  >6kj8D (D:)
  tvidhipaqigfkllslfkltetdqritiglndlikientflsedqvdqlalyapqatvn
  ridnyevvgksrpslperidnvlvcpnsncishaepvsssfavrkrandialkckyceke
  fshnvvlan
  

  
  
• Chain 'E':
  No sequence available.
  
  
• Chain 'F':
  Sequence, based on SEQRES records: (download)
  

  >6kj8F (F:)
  mthdnklqveaikrgtvidhipaqigfkllslfkltetdqritiglnlpsgemgrkdlik
  ientflsedqvdqlalyapqatvnridnyevvgksrpslperidnvlvcpnsncishaep
  vsssfavrkrandialkckycekefshnvvlan
  

  
  Sequence, based on observed residues (ATOM records): (download)
  

  >6kj8F (F:)
  aikrgtvidhipaqigfkllslfkltetdqritiglnlpsgemgrkdlikientflsedq
  vdqlalyapqatvnridnyevvgksrpslperidnvlvcpnsncishaepvsssfavrkr
  andialkckycekefshnvvlan