PDB entry 6jlq

View 6jlq on RCSB PDB site
Description: Crystal structure of human USP46-WDR48-WDR20 complex
Class: hydrolase
Keywords: Deubiquitinase, DUB, HYDROLASE, USP46
Deposited on 2019-03-06, released 2019-07-10
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-01-22, with a file datestamp of 2020-01-17.
Experiment type: XRAY
Resolution: 3.1 Å
R-factor: N/A
AEROSPACI score: 0.12 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Ubiquitin carboxyl-terminal hydrolase 46
    Species: Homo sapiens [TaxId:9606]
    Gene: USP46
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6jlqa_
  • Chain 'B':
    Compound: WD repeat-containing protein 48
    Species: Homo sapiens [TaxId:9606]
    Gene: WDR48
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: WD repeat-containing protein 20,highly similar to WD repeat protein 20,WD repeat-containing protein 20
    Species: Bos mutus [TaxId:72004]
    Gene: M91_05678
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8TBZ3 (Start-325)
      • linker (326-328)
      • linker (330)
    • Uniprot B3KQX8 (331-End)
    • Uniprot L8I535 (383-End)
  • Heterogens: ZN, GOL, PO4

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >6jlqA (A:)
    mgpeqfpinehyfglvnfgntcycnsvlqalyfcrpfrenvlaykaqqkkkenlltclad
    lfhsiatqkkkvgvippkkfisrlrkendlfdnymqqdaheflnyllntiadilqeekkq
    ekqngklkngnmnepaennkpeltwvheifqgtltnetrclncetvsskdedfldlsvdv
    eqntsithclrdfsntetlcseqkyycetccskqeaqkrmrvkklpmilalhlkrfkyme
    qlhrytklsyrvvfplelrlfntssdavnldrmydlvavvvhcgsgpnrghyitivkshg
    fwllfdddivekidaqaieefygltsdisknsesgyilfyqsrelehhhhhh
    

    Sequence, based on observed residues (ATOM records): (download)
    >6jlqA (A:)
    fglvnfgntcycnsvlqalyfcrpfrenvlaltcladlfhsiaippkkfisrlrkendlf
    dnymqqdaheflnyllntiadilqeekkqeltwvheifqgtltnetrclncetvsskded
    fldlsvdveqntsithclrdfsntetlcseqkyycetccskqeaqkrmrvkklpmilalh
    lkrfkymeqlhrytklsyrvvfplelrlfntssdavnldrmydlvavvvhcgsgpnrghy
    itivkshgfwllfdddivekidaqaieefygltsdisknsesgyilfyqsre
    

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    No sequence available.