PDB entry 6j8m

View 6j8m on RCSB PDB site
Description: Low-dose structure of bovine heart cytochrome c oxidase in the fully oxidized state determined using 30 keV X-ray
Class: oxidoreductase
Keywords: oxidoreductase, proton pump, heme, respiratory chain
Deposited on 2019-01-20, released 2019-06-26
The last revision prior to the SCOPe 2.07 freeze date was dated 2019-07-17, with a file datestamp of 2019-07-12.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cytochrome c oxidase subunit 1
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6j8ma_
  • Chain 'B':
    Compound: Cytochrome c oxidase subunit 2
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6j8mb1, d6j8mb2
  • Chain 'C':
    Compound: Cytochrome c oxidase subunit 3
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6j8mc_
  • Chain 'D':
    Compound: Cytochrome c oxidase subunit 4 isoform 1
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6j8md_
  • Chain 'E':
    Compound: Cytochrome c oxidase subunit 5A
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6j8me_
  • Chain 'F':
    Compound: Cytochrome c oxidase subunit 5B
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6j8mf_
  • Chain 'G':
    Compound: Cytochrome c oxidase subunit 6A2
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6j8mg_
  • Chain 'H':
    Compound: Cytochrome c oxidase subunit 6B1
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6j8mh_
  • Chain 'I':
    Compound: Cytochrome c oxidase subunit 6C
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6j8mi_
  • Chain 'J':
    Compound: Cytochrome c oxidase subunit 7A1
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6j8mj_
  • Chain 'K':
    Compound: Cytochrome c oxidase subunit 7B
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6j8mk_
  • Chain 'L':
    Compound: Cytochrome c oxidase subunit 7C
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6j8ml_
  • Chain 'M':
    Compound: Cytochrome c oxidase subunit 8B
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6j8mm_
  • Chain 'N':
    Compound: Cytochrome c oxidase subunit 1
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6j8mn_
  • Chain 'O':
    Compound: Cytochrome c oxidase subunit 2
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6j8mo1, d6j8mo2
  • Chain 'P':
    Compound: Cytochrome c oxidase subunit 3
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6j8mp_
  • Chain 'Q':
    Compound: Cytochrome c oxidase subunit 4 isoform 1
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6j8mq_
  • Chain 'R':
    Compound: Cytochrome c oxidase subunit 5A
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6j8mr_
  • Chain 'S':
    Compound: Cytochrome c oxidase subunit 5B
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6j8ms_
  • Chain 'T':
    Compound: Cytochrome c oxidase subunit 6A2
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6j8mt_
  • Chain 'U':
    Compound: Cytochrome c oxidase subunit 6B1
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6j8mu_
  • Chain 'V':
    Compound: Cytochrome c oxidase subunit 6C
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6j8mv_
  • Chain 'W':
    Compound: Cytochrome c oxidase subunit 7A1
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6j8mw_
  • Chain 'X':
    Compound: Cytochrome c oxidase subunit 7B
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6j8mx_
  • Chain 'Y':
    Compound: Cytochrome c oxidase subunit 7C
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6j8my_
  • Chain 'Z':
    Compound: Cytochrome c oxidase subunit 8B
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6j8mz_
  • Heterogens: HEA, CU, MG, NA, PGV, PER, TGL, CUA, CHD, PEK, CDL, DMU, PSC, ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6j8mA (A:)
mfinrwlfstnhkdigtlyllfgawagmvgtalslliraelgqpgtllgddqiynvvvta
hafvmiffmvmpimiggfgnwlvplmigapdmafprmnnmsfwllppsfllllassmvea
gagtgwtvypplagnlahagasvdltifslhlagvssilgainfittiinmkppamsqyq
tplfvwsvmitavllllslpvlaagitmlltdrnlnttffdpagggdpilyqhlfwffgh
pevyililpgfgmishivtyysgkkepfgymgmvwammsigflgfivwahhmftvgmdvd
trayftsatmiiaiptgvkvfswlatlhggnikwspammwalgfiflftvggltgivlan
ssldivlhdtyyvvahfhyvlsmgavfaimggfvhwfplfsgytlndtwakihfaimfvg
vnmtffpqhflglsgmprrysdypdaytmwntissmgsfisltavmlmvfiiweafaskr
evltvdltttnlewlngcpppyhtfeeptyvnlk

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6j8mB (B:)
maypmqlgfqdatspimeellhfhdhtlmivflisslvlyiislmlttklthtstmdaqe
vetiwtilpaiililialpslrilymmdeinnpsltvktmghqwywsyeytdyedlsfds
ymiptselkpgelrllevdnrvvlpmemtirmlvssedvlhswavpslglktdaipgrln
qttlmssrpglyygqcseicgsnhsfmpivlelvplkyfekwsasml

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6j8mC (C:)
mthqthayhmvnpspwpltgalsallmtsgltmwfhfnsmtllmiglttnmltmyqwwrd
virestfqghhtpavqkglrygmilfiisevlfftgffwafyhsslaptpelggcwpptg
ihplnplevpllntsvllasgvsitwahhslmegdrkhmlqalfititlgvyftllqase
yyeapftisdgvygstffvatgfhglhviigstflivcffrqlkfhftsnhhfgfeaaaw
ywhfvdvvwlflyvsiywwgs

    Sequence, based on observed residues (ATOM records): (download) 
    >6j8mC (C:)
hqthayhmvnpspwpltgalsallmtsgltmwfhfnsmtllmiglttnmltmyqwwrdvi
restfqghhtpavqkglrygmilfiisevlfftgffwafyhsslaptpelggcwpptgih
plnplevpllntsvllasgvsitwahhslmegdrkhmlqalfititlgvyftllqaseyy
eapftisdgvygstffvatgfhglhviigstflivcffrqlkfhftsnhhfgfeaaawyw
hfvdvvwlflyvsiywwgs

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6j8mD (D:)
ahgsvvksedyalpsyvdrrdyplpdvahvknlsasqkalkekekaswsslsidekvely
rlkfkesfaemnrstnewktvvgaamffigftallliwekhyvygpiphtfeeewvakqt
krmldmkvapiqgfsakwdydknewkk

    Sequence, based on observed residues (ATOM records): (download) 
    >6j8mD (D:)
svvksedyalpsyvdrrdyplpdvahvknlsasqkalkekekaswsslsidekvelyrlk
fkesfaemnrstnewktvvgaamffigftallliwekhyvygpiphtfeeewvakqtkrm
ldmkvapiqgfsakwdydknewkk

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >6j8mE (E:)
shgshetdeefdarwvtyfnkpdidawelrkgmntlvgydlvpepkiidaalracrrlnd
fasavrilevvkdkagphkeiypyviqelrptlnelgistpeelgldkv

    Sequence, based on observed residues (ATOM records): (download) 
    >6j8mE (E:)
hetdeefdarwvtyfnkpdidawelrkgmntlvgydlvpepkiidaalracrrlndfasa
vrilevvkdkagphkeiypyviqelrptlnelgistpeelgldkv

  • Chain 'F':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6j8mF (F:)
asgggvptdeeqatglerevmlaarkgqdpynilapkatsgtkedpnlvpsitnkrivgc
iceednstviwfwlhkgeaqrcpscgthyklvphqlah

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >6j8mG (G:)
asaakgdhggtgartwrfltfglalpsvalctlnswlhsghrerpafipyhhlrirtkpf
swgdgnhtffhnprvnplptgyekp

    Sequence, based on observed residues (ATOM records): (download) 
    >6j8mG (G:)
asaakgdhggtgartwrfltfglalpsvalctlnswlhsghrerpafipyhhlrirtkpf
swgdgnhtffhnprvnplptgyek

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >6j8mH (H:)
aediqakiknyqtapfdsrfpnqnqtrncwqnyldfhrcekamtakggdvsvcewyrrvy
kslcpiswvstwddrraegtfpgki

    Sequence, based on observed residues (ATOM records): (download) 
    >6j8mH (H:)
kiknyqtapfdsrfpnqnqtrncwqnyldfhrcekamtakggdvsvcewyrrvykslcpi
swvstwddrraegtfpgki

  • Chain 'I':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6j8mI (I:)
stalakpqmrgllarrlrfhivgafmvslgfatfykfavaekrkkayadfyrnydsmkdf
eemrkagifqsak

  • Chain 'J':
    Sequence, based on SEQRES records: (download) 
    >6j8mJ (J:)
fenrvaekqklfqednglpvhlkggatdnilyrvtmtlclggtlyslyclgwasfphkk

    Sequence, based on observed residues (ATOM records): (download) 
    >6j8mJ (J:)
fenrvaekqklfqednglpvhlkggatdnilyrvtmtlclggtlyslyclgwasfphk

  • Chain 'K':
    Sequence, based on SEQRES records: (download) 
    >6j8mK (K:)
ihqkrapdfhdkygnavlasgatfcvavwvymatqigiewnpspvgrvtpkewreq

    Sequence, based on observed residues (ATOM records): (download) 
    >6j8mK (K:)
apdfhdkygnavlasgatfcvavwvymatqigiewnpspvgrvtpkewr

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >6j8mL (L:)
shyeegpgknipfsvenkwrllammtlffgsgfaapffivrhqllkk

    Sequence, based on observed residues (ATOM records): (download) 
    >6j8mL (L:)
hyeegpgknipfsvenkwrllammtlffgsgfaapffivrhqllkk

  • Chain 'M':
    Sequence, based on SEQRES records: (download) 
    >6j8mM (M:)
itakpaktptspkeqaiglsvtflsfllpagwvlyhldnykkssaa

    Sequence, based on observed residues (ATOM records): (download) 
    >6j8mM (M:)
itakpaktptspkeqaiglsvtflsfllpagwvlyhldnykks

  • Chain 'N':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6j8mN (N:)
mfinrwlfstnhkdigtlyllfgawagmvgtalslliraelgqpgtllgddqiynvvvta
hafvmiffmvmpimiggfgnwlvplmigapdmafprmnnmsfwllppsfllllassmvea
gagtgwtvypplagnlahagasvdltifslhlagvssilgainfittiinmkppamsqyq
tplfvwsvmitavllllslpvlaagitmlltdrnlnttffdpagggdpilyqhlfwffgh
pevyililpgfgmishivtyysgkkepfgymgmvwammsigflgfivwahhmftvgmdvd
trayftsatmiiaiptgvkvfswlatlhggnikwspammwalgfiflftvggltgivlan
ssldivlhdtyyvvahfhyvlsmgavfaimggfvhwfplfsgytlndtwakihfaimfvg
vnmtffpqhflglsgmprrysdypdaytmwntissmgsfisltavmlmvfiiweafaskr
evltvdltttnlewlngcpppyhtfeeptyvnlk

  • Chain 'O':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6j8mO (O:)
maypmqlgfqdatspimeellhfhdhtlmivflisslvlyiislmlttklthtstmdaqe
vetiwtilpaiililialpslrilymmdeinnpsltvktmghqwywsyeytdyedlsfds
ymiptselkpgelrllevdnrvvlpmemtirmlvssedvlhswavpslglktdaipgrln
qttlmssrpglyygqcseicgsnhsfmpivlelvplkyfekwsasml

  • Chain 'P':
    Sequence, based on SEQRES records: (download) 
    >6j8mP (P:)
mthqthayhmvnpspwpltgalsallmtsgltmwfhfnsmtllmiglttnmltmyqwwrd
virestfqghhtpavqkglrygmilfiisevlfftgffwafyhsslaptpelggcwpptg
ihplnplevpllntsvllasgvsitwahhslmegdrkhmlqalfititlgvyftllqase
yyeapftisdgvygstffvatgfhglhviigstflivcffrqlkfhftsnhhfgfeaaaw
ywhfvdvvwlflyvsiywwgs

    Sequence, based on observed residues (ATOM records): (download) 
    >6j8mP (P:)
hqthayhmvnpspwpltgalsallmtsgltmwfhfnsmtllmiglttnmltmyqwwrdvi
restfqghhtpavqkglrygmilfiisevlfftgffwafyhsslaptpelggcwpptgih
plnplevpllntsvllasgvsitwahhslmegdrkhmlqalfititlgvyftllqaseyy
eapftisdgvygstffvatgfhglhviigstflivcffrqlkfhftsnhhfgfeaaawyw
hfvdvvwlflyvsiywwgs

  • Chain 'Q':
    Sequence, based on SEQRES records: (download) 
    >6j8mQ (Q:)
ahgsvvksedyalpsyvdrrdyplpdvahvknlsasqkalkekekaswsslsidekvely
rlkfkesfaemnrstnewktvvgaamffigftallliwekhyvygpiphtfeeewvakqt
krmldmkvapiqgfsakwdydknewkk

    Sequence, based on observed residues (ATOM records): (download) 
    >6j8mQ (Q:)
svvksedyalpsyvdrrdyplpdvahvknlsasqkalkekekaswsslsidekvelyrlk
fkesfaemnrstnewktvvgaamffigftallliwekhyvygpiphtfeeewvakqtkrm
ldmkvapiqgfsakwdydknewkk

  • Chain 'R':
    Sequence, based on SEQRES records: (download) 
    >6j8mR (R:)
shgshetdeefdarwvtyfnkpdidawelrkgmntlvgydlvpepkiidaalracrrlnd
fasavrilevvkdkagphkeiypyviqelrptlnelgistpeelgldkv

    Sequence, based on observed residues (ATOM records): (download) 
    >6j8mR (R:)
hetdeefdarwvtyfnkpdidawelrkgmntlvgydlvpepkiidaalracrrlndfasa
vrilevvkdkagphkeiypyviqelrptlnelgistpeelgldkv

  • Chain 'S':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6j8mS (S:)
asgggvptdeeqatglerevmlaarkgqdpynilapkatsgtkedpnlvpsitnkrivgc
iceednstviwfwlhkgeaqrcpscgthyklvphqlah

  • Chain 'T':
    Sequence, based on SEQRES records: (download) 
    >6j8mT (T:)
asaakgdhggtgartwrfltfglalpsvalctlnswlhsghrerpafipyhhlrirtkpf
swgdgnhtffhnprvnplptgyekp

    Sequence, based on observed residues (ATOM records): (download) 
    >6j8mT (T:)
asaakgdhggtgartwrfltfglalpsvalctlnswlhsghrerpafipyhhlrirtkpf
swgdgnhtffhnprvnplptgyek

  • Chain 'U':
    Sequence, based on SEQRES records: (download) 
    >6j8mU (U:)
aediqakiknyqtapfdsrfpnqnqtrncwqnyldfhrcekamtakggdvsvcewyrrvy
kslcpiswvstwddrraegtfpgki

    Sequence, based on observed residues (ATOM records): (download) 
    >6j8mU (U:)
kiknyqtapfdsrfpnqnqtrncwqnyldfhrcekamtakggdvsvcewyrrvykslcpi
swvstwddrraegtfpgki

  • Chain 'V':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6j8mV (V:)
stalakpqmrgllarrlrfhivgafmvslgfatfykfavaekrkkayadfyrnydsmkdf
eemrkagifqsak

  • Chain 'W':
    Sequence, based on SEQRES records: (download) 
    >6j8mW (W:)
fenrvaekqklfqednglpvhlkggatdnilyrvtmtlclggtlyslyclgwasfphkk

    Sequence, based on observed residues (ATOM records): (download) 
    >6j8mW (W:)
fenrvaekqklfqednglpvhlkggatdnilyrvtmtlclggtlyslyclgwasfphk

  • Chain 'X':
    Sequence, based on SEQRES records: (download) 
    >6j8mX (X:)
ihqkrapdfhdkygnavlasgatfcvavwvymatqigiewnpspvgrvtpkewreq

    Sequence, based on observed residues (ATOM records): (download) 
    >6j8mX (X:)
apdfhdkygnavlasgatfcvavwvymatqigiewnpspvgrvtpkewr

  • Chain 'Y':
    Sequence, based on SEQRES records: (download) 
    >6j8mY (Y:)
shyeegpgknipfsvenkwrllammtlffgsgfaapffivrhqllkk

    Sequence, based on observed residues (ATOM records): (download) 
    >6j8mY (Y:)
hyeegpgknipfsvenkwrllammtlffgsgfaapffivrhqllkk

  • Chain 'Z':
    Sequence, based on SEQRES records: (download) 
    >6j8mZ (Z:)
itakpaktptspkeqaiglsvtflsfllpagwvlyhldnykkssaa

    Sequence, based on observed residues (ATOM records): (download) 
    >6j8mZ (Z:)
itakpaktptspkeqaiglsvtflsfllpagwvlyhldnykks