PDB entry 6isu

View 6isu on RCSB PDB site
Description: Crystal structure of Lys27-linked di-ubiquitin in complex with its selective interacting protein UCHL3
Class: hydrolase
Keywords: Ubiquitination, UCHL3, Lys27-linked di-ubiquitin, HYDROLASE
Deposited on 2018-11-19, released 2019-02-06
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-03-06, with a file datestamp of 2019-03-01.
Experiment type: XRAY
Resolution: 1.87 Å
R-factor: N/A
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Ubiquitin carboxyl-terminal hydrolase isozyme L3
    Species: Homo sapiens [TaxId:9606]
    Gene: UCHL3
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6isua_
  • Chain 'B':
    Compound: Ubiquitin
    Species: Homo sapiens [TaxId:9606]
    Gene: UBB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6isub_
  • Chain 'C':
    Compound: Ubiquitin
    Species: Homo sapiens [TaxId:9606]
    Gene: UBB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6isuc_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6isuA (A:)
megqrwlpleanpevtnqflkqlglhpnwqfvdvygmdpellsmvprpvcavlllfpite
kyevfrteeeekiksqgqdvtssvyfmkqtisnacgtiglihaiannkdkmhfesgstlk
kfleesvsmspeerarylenydairvthetsahegqteapsidekvdlhfialvhvdghl
yeldgrkpfpinhgetsdetlledaievckkfmerdpdelrfnaialsaa

    Sequence, based on observed residues (ATOM records): (download) 
    >6isuA (A:)
qrwlpleanpevtnqflkqlglhpnwqfvdvygmdpellsmvprpvcavlllfpitekye
vfrteeeekiksqgqdvtssvyfmkqtisnacgtiglihaiannkdkmhfesgstlkkfl
eesvsmspeerarylenydairvthetsahegqteapsidekvdlhfialvhvdghlyel
dgrkpfpinhgetsdetlledaievckkfmerdpdelrfnaialsaa

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6isuB (B:)
mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
iqkestlhlvlrlrgg

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6isuC (C:)
mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
iqkestlhlvlrlrgg