PDB entry 6icg

View 6icg on RCSB PDB site
Description: Grb2 SH2 domain in phosphopeptide free form
Class: signaling protein
Keywords: Src homology 2 domain, phosphorylated tyrosine, Adapter protein, SIGNALING PROTEIN
Deposited on 2018-09-06, released 2019-07-17
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-07-17, with a file datestamp of 2019-07-12.
Experiment type: XRAY
Resolution: 1.15 Å
R-factor: N/A
AEROSPACI score: 0.69 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Growth factor receptor-bound protein 2
    Species: Homo sapiens [TaxId:9606]
    Gene: GRB2, ASH
    Database cross-references and differences (RAF-indexed):
    • Uniprot P62993 (2-94)
      • expression tag (0-1)
    Domains in SCOPe 2.08: d6icga1, d6icga2
  • Chain 'B':
    Compound: Growth factor receptor-bound protein 2
    Species: Homo sapiens [TaxId:9606]
    Gene: GRB2, ASH
    Database cross-references and differences (RAF-indexed):
    • Uniprot P62993 (2-94)
      • expression tag (0-1)
    Domains in SCOPe 2.08: d6icgb1, d6icgb2
  • Heterogens: SO4, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >6icgA (A:)
    gswffgkiprakaeemlskqrhdgafliresesapgdfslsvkfgndvqhfkvlrdgagk
    yflwvvkfnslnelvdyhrstsvsrnqqiflrdie
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >6icgB (B:)
    gswffgkiprakaeemlskqrhdgafliresesapgdfslsvkfgndvqhfkvlrdgagk
    yflwvvkfnslnelvdyhrstsvsrnqqiflrdie