PDB entry 6i10

View 6i10 on RCSB PDB site
Description: crystal structure of fascin in complex with compound 2
Class: structural protein
Keywords: actin bundling, small molecule inhibition, STRUCTURAL PROTEIN
Deposited on 2018-10-27, released 2019-02-27
The last revision prior to the SCOPe 2.07 freeze date was dated 2019-02-27, with a file datestamp of 2019-02-22.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: N/A
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: fascin
    Species: Homo sapiens [TaxId:9606]
    Gene: FSCN1, FAN1, HSN, SNL
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6i10a1, d6i10a2, d6i10a3, d6i10a4
  • Heterogens: GZK, ACT, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >6i10A (A:)
    mtangtaeavqiqfglincgnkyltaeafgfkvnasasslkkkqiwtleqppdeagsaav
    clrshlgrylaadkdgnvtcerevpgpdcrflivahddgrwslqseahrryfggtedrls
    cfaqtvspaekwsvhiamhpqvniysvtrkryahlsarpadeiavdrdvpwgvdslitla
    fqdqrysvqtadhrflrhdgrlvarpepatgytlefrsgkvafrdcegrylapsgpsgtl
    kagkatkvgkdelfaleqscaqvvlqaanernvstrqgmdlsanqdeetdqetfqleidr
    dtkkcafrthtgkywtltatggvqstassknascyfdiewrdrritlrasngkfvtskkn
    gqlaasvetagdselflmklinrpiivfrgehgfigcrkvtgtldanrssydvfqlefnd
    gaynikdstgkywtvgsdsavtssgdtpvdfffefcdynkvaikvggrylkgdhagvlka
    saetvdpaslwey
    

    Sequence, based on observed residues (ATOM records): (download)
    >6i10A (A:)
    qiqfglincgnkyltaeafgfkvnasasslkkkqiwtleqppdeagsaavclrshlgryl
    aadkdgnvtcerevpgpdcrflivahddgrwslqseahrryfggtedrlscfaqtvspae
    kwsvhiamhpqvniysvtrkryahlsarpadeiavdrdvpwgvdslitlafqdqrysvqt
    adhrflrhdgrlvarpepatgytlefrsgkvafrdcegrylapsgpsgtlkagkatkvgk
    delfaleqscaqvvlqaanernvstrqgmdlsanqdeetdqetfqleidrdtkkcafrth
    tgkywtltatggvqstassknascyfdiewrdrritlrasngkfvtskkngqlaasveta
    gdselflmklinrpiivfrgehgfigcrkvtgtldanrssydvfqlefndgaynikdstg
    kywtvgsdsavtssgdtpvdfffefcdynkvaikvggrylkgdhagvlkasaetvdpasl
    wey