PDB entry 6glc

View 6glc on RCSB PDB site
Description: Structure of phospho-Parkin bound to phospho-ubiquitin
Class: ligase
Keywords: ubiquitin, Parkin, phospho-ubiquitin, Parkinson's disease, E3 ligase, RBR domain, mitophagy, LIGASE
Deposited on 2018-05-23, released 2018-06-13
The last revision prior to the SCOPe 2.07 freeze date was dated 2018-06-13, with a file datestamp of 2018-06-08.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: N/A
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: E3 ubiquitin-protein ligase parkin
    Species: Homo sapiens [TaxId:9606]
    Gene: PRKN, PARK2
    Database cross-references and differences (RAF-indexed):
    • Uniprot O60260 (2-End)
      • expression tag (1)
      • engineered mutation (348)
  • Chain 'B':
    Compound: Polyubiquitin-B
    Species: Homo sapiens [TaxId:9606]
    Gene: UBB
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0CG47 (0-75)
      • engineered mutation (75)
    Domains in SCOPe 2.07: d6glcb_
  • Heterogens: ZN, GOL, MPD, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >6glcB (B:)
    mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
    iqkestlhlvlrlrgx