PDB entry 6fw0

View 6fw0 on RCSB PDB site
Description: Crystal structure of human monoamine oxidase B (MAO B) in complex with chlorophenyl-chromone-carboxamide
Class: flavoprotein
Keywords: Parkinson's disease, drug design, chromone, inhibitor, FLAVOPROTEIN
Deposited on 2018-03-05, released 2018-04-25
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-05-23, with a file datestamp of 2018-05-18.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: N/A
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: amine oxidase [flavin-containing] b
    Species: Homo sapiens [TaxId:9606]
    Gene: MAOB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6fw0a1, d6fw0a2
  • Chain 'B':
    Compound: amine oxidase [flavin-containing] b
    Species: Homo sapiens [TaxId:9606]
    Gene: MAOB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6fw0b1, d6fw0b2
  • Heterogens: FAD, E92, C15, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6fw0A (A:)
msnkcdvvvvgggisgmaaakllhdsglnvvvleardrvggrtytlrnqkvkyvdlggsy
vgptqnrilrlakelgletykvneverlihhvkgksypfrgpfppvwnpityldhnnfwr
tmddmgreipsdapwkaplaeewdnmtmkelldklcwtesakqlatlfvnlcvtaethev
salwflwyvkqcggttriisttnggqerkfvggsgqvserimdllgdrvklerpviyidq
trenvlvetlnhemyeakyvisaipptlgmkihfnpplpmmrnqmitrvplgsvikcivy
ykepfwrkkdycgtmiidgeeapvaytlddtkpegnyaaimgfilahkarklarltkeer
lkklcelyakvlgslealepvhyeeknwceeqysggcyttyfppgiltqygrvlrqpvdr
iyfagtetathwsgymegaveageraareilhamgkipedeiwqsepesvdvpaqpittt
flerhlpsvpgllrliglttifsatalgflahkrgllvrv

    Sequence, based on observed residues (ATOM records): (download) 
    >6fw0A (A:)
snkcdvvvvgggisgmaaakllhdsglnvvvleardrvggrtytlrnqkvkyvdlggsyv
gptqnrilrlakelgletykvneverlihhvkgksypfrgpfppvwnpityldhnnfwrt
mddmgreipsdapwkaplaeewdnmtmkelldklcwtesakqlatlfvnlcvtaethevs
alwflwyvkqcggttriisttnggqerkfvggsgqvserimdllgdrvklerpviyidqt
renvlvetlnhemyeakyvisaipptlgmkihfnpplpmmrnqmitrvplgsvikcivyy
kepfwrkkdycgtmiidgeeapvaytlddtkpegnyaaimgfilahkarklarltkeerl
kklcelyakvlgslealepvhyeeknwceeqysggcyttyfppgiltqygrvlrqpvdri
yfagtetathwsgymegaveageraareilhamgkipedeiwqsepesvdvpaqpitttf
lerhlpsvpgllrligltti

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6fw0B (B:)
msnkcdvvvvgggisgmaaakllhdsglnvvvleardrvggrtytlrnqkvkyvdlggsy
vgptqnrilrlakelgletykvneverlihhvkgksypfrgpfppvwnpityldhnnfwr
tmddmgreipsdapwkaplaeewdnmtmkelldklcwtesakqlatlfvnlcvtaethev
salwflwyvkqcggttriisttnggqerkfvggsgqvserimdllgdrvklerpviyidq
trenvlvetlnhemyeakyvisaipptlgmkihfnpplpmmrnqmitrvplgsvikcivy
ykepfwrkkdycgtmiidgeeapvaytlddtkpegnyaaimgfilahkarklarltkeer
lkklcelyakvlgslealepvhyeeknwceeqysggcyttyfppgiltqygrvlrqpvdr
iyfagtetathwsgymegaveageraareilhamgkipedeiwqsepesvdvpaqpittt
flerhlpsvpgllrliglttifsatalgflahkrgllvrv

    Sequence, based on observed residues (ATOM records): (download) 
    >6fw0B (B:)
snkcdvvvvgggisgmaaakllhdsglnvvvleardrvggrtytlrnqkvkyvdlggsyv
gptqnrilrlakelgletykvneverlihhvkgksypfrgpfppvwnpityldhnnfwrt
mddmgreipsdapwkaplaeewdnmtmkelldklcwtesakqlatlfvnlcvtaethevs
alwflwyvkqcggttriisttnggqerkfvggsgqvserimdllgdrvklerpviyidqt
renvlvetlnhemyeakyvisaipptlgmkihfnpplpmmrnqmitrvplgsvikcivyy
kepfwrkkdycgtmiidgeeapvaytlddtkpegnyaaimgfilahkarklarltkeerl
kklcelyakvlgslealepvhyeeknwceeqysggcyttyfppgiltqygrvlrqpvdri
yfagtetathwsgymegaveageraareilhamgkipedeiwqsepesvdvpaqpitttf
lerhlpsvpgllrli