PDB entry 6fut

View 6fut on RCSB PDB site
Description: Complement factor D in complex with the inhibitor (S)-3'-(aminomethyl)-N-(1,2,3,4-tetrahydronaphthalen-1-yl)-[1,1'-biphenyl]-3-carboxamide
Class: hydrolase
Keywords: protease, inhibitor complex, HYDROLASE
Deposited on 2018-02-27, released 2018-06-06
The last revision prior to the SCOPe 2.07 freeze date was dated 2018-06-06, with a file datestamp of 2018-06-01.
Experiment type: XRAY
Resolution: 1.5 Å
R-factor: N/A
AEROSPACI score: 0.48 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: complement factor d
    Species: Homo sapiens [TaxId:9606]
    Gene: CFD, DF, PFD
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00746 (0-227)
      • expression tag (228-231)
    Domains in SCOPe 2.07: d6futa1, d6futa2
  • Heterogens: E82, SIN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6futA (A:)
ilggreaeaharpymasvqlngahlcggvlvaeqwvlsaahcledaadgkvqvllgahsl
sqpepskrlydvlravphpdsqpdtidhdllllqlsekatlgpavrplpwqrvdrdvapg
tlcdvagwgivnhagrrpdslqhvllpvldratcnrrthhdgaiterlmcaesnrrdsck
gdsggplvcggvlegvvtsgsrvcgnrkkpgiytrvasyaawidsvlasaaa

    Sequence, based on observed residues (ATOM records): (download) 
    >6futA (A:)
ilggreaeaharpymasvqlngahlcggvlvaeqwvlsaahclegkvqvllgahslsqpe
pskrlydvlravphpdsqpdtidhdllllqlsekatlgpavrplpwqrvdrdvapgtlcd
vagwgivnhagrrpdslqhvllpvldratcnrrthhdgaiterlmcaesnrrdsckgdsg
gplvcggvlegvvtsgsrvcgnrkkpgiytrvasyaawidsvlasaaa