PDB entry 6fmf

View 6fmf on RCSB PDB site
Description: Neuropilin-1 b1 domain in complex with EG01377; 2.8 Angstrom structure
Class: signaling protein
Keywords: small molecule inhibitor, VEGF signaling, semaphorin signaling, angiogenesis, discoiding domain, signaling protein
Deposited on 2018-01-31, released 2018-10-17
The last revision prior to the SCOPe 2.07 freeze date was dated 2018-10-17, with a file datestamp of 2018-10-12.
Experiment type: XRAY
Resolution: 2.81 Å
R-factor: N/A
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Neuropilin-1
    Species: Homo sapiens [TaxId:9606]
    Gene: NRP1, NRP, VEGF165R
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6fmfa_
  • Heterogens: DUE, TFA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >6fmfA (A:)
    ghmfkcmealgmesgeihsdqitassqystnwsaersrlnypengwtpgedsyrewiqvd
    lgllrfvtavgtqgaisketkkkyyvktykidvssngedwitikegnkpvlfqgntnptd
    vvvavfpkplitrfvrikpatwetgismrfevygckit
    

    Sequence, based on observed residues (ATOM records): (download)
    >6fmfA (A:)
    fkcmealgmesgeihsdqitassqystnwsaersrlnypengwtpgedsyrewiqvdlgl
    lrfvtavgtqgaisketkkkyyvktykidvssngedwitikegnkpvlfqgntnptdvvv
    avfpkplitrfvrikpatwetgismrfevygckit