PDB entry 6fin

View 6fin on RCSB PDB site
Description: DDR1, 3-[(3-cyclopropyl-1,2,4-oxadiazol-5-yl)methyl]-8-(1H-indazole-5-carbonyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one, 1.670A, P1211, Rfree=22.8%
Class: transferase
Keywords: rtk, receptor tyrosine kinase, collagen, discoidin domain;, transferase
Deposited on 2018-01-19, released 2018-11-28
The last revision prior to the SCOPe 2.07 freeze date was dated 2018-11-28, with a file datestamp of 2018-11-23.
Experiment type: XRAY
Resolution: 1.67 Å
R-factor: N/A
AEROSPACI score: 0.42 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: epithelial discoidin domain-containing receptor 1
    Species: Homo sapiens [TaxId:9606]
    Gene: DDR1, CAK, EDDR1, NEP, NTRK4, PTK3A, RTK6, TRKE
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6fina_
  • Heterogens: IOD, DJQ, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >6finA (A:)
    pgavgdgpprvdfprsrlrfkeklgegqfgevhlcevdspqdlvsldfplnvrkghpllv
    avkilrpdatknarndflkevkimsrlkdpniirllgvcvqddplcmitdymengdlnqf
    lsahqledkaaegapgdptisypmllhvaaqiasgmrylatlnfvhrdlatrnclvgenf
    tikiadfgmsrnlyagdyyrvqgravlpirwmawecilmgkfttasdvwafgvtlwevlm
    lcraqpfgqltdeqvienageffrdqgrqvylsrppacpqglyelmlrcwsreseqrppf
    sqlhrflaedalntvhhhhhh
    

    Sequence, based on observed residues (ATOM records): (download)
    >6finA (A:)
    vdfprsrlrfkeklgegqfgevhlcevdspqdlvsplnvrkghpllvavkilrpdatkna
    rndflkevkimsrlkdpniirllgvcvqddplcmitdymengdlnqflsahqledkaapt
    isypmllhvaaqiasgmrylatlnfvhrdlatrnclvgenftikiadfgmsrnlyagdyy
    rvqgravlpirwmawecilmgkfttasdvwafgvtlwevlmlcraqpfgqltdeqviena
    geffrdqgrqvylsrppacpqglyelmlrcwsreseqrppfsqlhrflaedaln