PDB entry 6fft
View 6fft on RCSB PDB site
Description: Neutron structure of human transthyretin (TTR) S52P mutant in complex with tafamidis at room temperature to 2A resolution (quasi-Laue)
Class: transport protein
Keywords: homotetramer, prealbumin, mutant-drug complex, TRANSPORT PROTEIN
Deposited on
2018-01-09, released
2019-01-02
The last revision prior to the SCOPe 2.08 freeze date was dated
2019-03-20, with a file datestamp of
2019-03-15.
Experiment type: XRAYNEUT
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.32
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Transthyretin
Species: Homo sapiens [TaxId:9606]
Gene: TTR, PALB
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d6ffta_ - Chain 'B':
Compound: Transthyretin
Species: Homo sapiens [TaxId:9606]
Gene: TTR, PALB
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d6fftb_ - Heterogens: 3MI, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>6fftA (A:)
gamgptgtgeskcplmvkvldavrgspainvavhvfrkaaddtwepfasgktsepgelhg
ltteeefvegiykveidtksywkalgispfhehaevvftandsgprrytiaallspysys
ttavvtnpke
Sequence, based on observed residues (ATOM records): (download)
>6fftA (A:)
cplmvkvldavrgspainvavhvfrkaaddtwepfasgktsepgelhgltteeefvegiy
kveidtksywkalgispfhehaevvftandsgprrytiaallspysysttavvtnp
- Chain 'B':
Sequence, based on SEQRES records: (download)
>6fftB (B:)
gamgptgtgeskcplmvkvldavrgspainvavhvfrkaaddtwepfasgktsepgelhg
ltteeefvegiykveidtksywkalgispfhehaevvftandsgprrytiaallspysys
ttavvtnpke
Sequence, based on observed residues (ATOM records): (download)
>6fftB (B:)
cplmvkvldavrgspainvavhvfrkaaddtwepfasgktsepgelhgltteeefvegiy
kveidtksywkalgispfhehaevvftandsgprrytiaallspysysttavvtnp