PDB entry 6f5q
View 6f5q on RCSB PDB site
Description: Crystal Structure of KDM4D with GF026 ligand
Class: oxidoreductase
Keywords: KDM4D, KDM4, ligand binding, ligand optimization, drug development, inhibitor design, cancer, epigenetics, OXIDOREDUCTASE
Deposited on
2017-12-02, released
2018-12-12
The last revision prior to the SCOPe 2.08 freeze date was dated
2018-12-12, with a file datestamp of
2018-12-07.
Experiment type: XRAY
Resolution: 1.43 Å
R-factor: N/A
AEROSPACI score: 0.52
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Lysine-specific demethylase 4D
Species: Homo sapiens [TaxId:9606]
Gene: KDM4D, JHDM3D, JMJD2D
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d6f5qa_ - Heterogens: ZN, CL, EDO, SO4, NI, CTK, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>6f5qA (A:)
metmkskancaqnpncnimifhptkeefndfdkyiaymesqgahraglakiippkewkar
etydniseiliatplqqvasgragvftqyhkkkkamtvgeyrhlanskkyqtpphqnfed
lerkywknriynspiygadisgslfdentkqwnlghlgtiqdllekecgvviegvntpyl
yfgmwkttfawhtedmdlysinylhlgepktwyvvppehgqrlerlarelfpgssrgcga
flrhkvalisptvlkengipfnritqeagefmvtfpygyhagfnhgfncaeainfatprw
idygkmasqcscgearvtfsmdafvrilqperydlwkrgqdr
Sequence, based on observed residues (ATOM records): (download)
>6f5qA (A:)
aqnpncnimifhptkeefndfdkyiaymesqgahraglakiippkewkaretydniseil
iatplqqvasgragvftqyhkkkkamtvgeyrhlanskkyqtpphqnfedlerkywknri
ynspiygadisgslfdentkqwnlghlgtiqdllekecgvviegvntpylyfgmwkttfa
whtedmdlysinylhlgepktwyvvppehgqrlerlarelfpgssrgcgaflrhkvalis
ptvlkengipfnritqeagefmvtfpygyhagfnhgfncaeainfatprwidygkmasqc
scgearvtfsmdafvrilqperydlwkrgq