PDB entry 6e63

View 6e63 on RCSB PDB site
Description: Crystal structure of malaria transmission-blocking antigen Pfs48/45 6C in complex with antibody TB31F
Class: immune system
Keywords: malaria, transmission-blocking, antigen, antibody, IMMUNE SYSTEM
Deposited on 2018-07-23, released 2018-11-28
The last revision prior to the SCOPe 2.07 freeze date was dated 2018-11-28, with a file datestamp of 2018-11-23.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: N/A
AEROSPACI score: 0.19 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Pf48/45
    Species: Plasmodium falciparum [TaxId:5833]
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: TB31F Fab heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6E63 (0-End)
  • Chain 'C':
    Compound: TB31F Fab light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6E63 (0-End)
    Domains in SCOPe 2.07: d6e63c1, d6e63c2
  • Chain 'H':
    Compound: TB31F Fab heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6E63 (0-221)
  • Chain 'L':
    Compound: TB31F Fab light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6E63 (0-214)
    Domains in SCOPe 2.07: d6e63l1, d6e63l2
  • Chain 'P':
    Compound: Pf48/45
    Species: Plasmodium falciparum [TaxId:5833]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >6e63C (C:)
    nfmltqphsvsespgktvtisctrstgnigsnyvswyqqrpgsspttviyrddqrpsgvp
    drfsgsidrssnsasltisglktedeadyychsystgmyifgggtkltvlgqpkaapsvt
    lfppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaass
    ylsltpeqwkshrsyscqvthegstvektvaptec
    

    Sequence, based on observed residues (ATOM records): (download)
    >6e63C (C:)
    nfmltqphsvsespgktvtisctrstgnigsnyvswyqqrpgsspttviyrddqrpsgvp
    drfsgsidrssnsasltisglktedeadyychsystgmyifgggtkltvlgqpkaapsvt
    lfppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaass
    ylsltpeqwkshrsyscqvthegstvektvap
    

  • Chain 'H':
    No sequence available.

  • Chain 'L':
    Sequence; same for both SEQRES and ATOM records: (download)
    >6e63L (L:)
    nfmltqphsvsespgktvtisctrstgnigsnyvswyqqrpgsspttviyrddqrpsgvp
    drfsgsidrssnsasltisglktedeadyychsystgmyifgggtkltvlgqpkaapsvt
    lfppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaass
    ylsltpeqwkshrsyscqvthegstvektvaptec
    

  • Chain 'P':
    No sequence available.