PDB entry 6dxl
View 6dxl on RCSB PDB site
Description: Linked amidobenzimidazole STING agonist
Class: immune system/agonist
Keywords: agonist, DNA-sensor, cGAS, TBK1, IMMUNE SYSTEM, immune system-agonist complex
Deposited on
2018-06-29, released
2018-11-07
The last revision prior to the SCOPe 2.08 freeze date was dated
2019-01-02, with a file datestamp of
2018-12-28.
Experiment type: XRAY
Resolution: 2.45 Å
R-factor: N/A
AEROSPACI score: 0.22
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Stimulator of interferon protein
Species: Homo sapiens [TaxId:9606]
Gene: STING, LOC340061, hCG_1782396
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d6dxla_ - Chain 'B':
Compound: Stimulator of interferon protein
Species: Homo sapiens [TaxId:9606]
Gene: STING, LOC340061, hCG_1782396
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d6dxlb_ - Heterogens: HG4, CA, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>6dxlA (A:)
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qysqagfsredrleqaklfcrtlediladapesqnncrliayqepaddssfslsqevlrh
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Sequence, based on observed residues (ATOM records): (download)
>6dxlA (A:)
fnvahglawsyyigylrlilpelqarirtynqhynnllrgavsqrlyillpldcgvpdnl
smadpnirfldklpqqysnsiyellengqragtcvleyatplqtlfamsqysqagfsred
rleqaklfcrtlediladapesqnncrliayqepadfslsqevlrhlrqeekeevtv
- Chain 'B':
Sequence, based on SEQRES records: (download)
>6dxlB (B:)
fnvahglawsyyigylrlilpelqarirtynqhynnllrgavsqrlyillpldcgvpdnl
smadpnirfldklpqqtgdragikdrvysnsiyellengqragtcvleyatplqtlfams
qysqagfsredrleqaklfcrtlediladapesqnncrliayqepaddssfslsqevlrh
lrqeekeevtv
Sequence, based on observed residues (ATOM records): (download)
>6dxlB (B:)
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smadpnirfldklpqqtvysnsiyellengqragtcvleyatplqtlfamsqysqagfsr
edrleqaklfcrtlediladapesqnncrliayqepssfslsqevlrhlrqeekeevtv