PDB entry 6duc
View 6duc on RCSB PDB site
Description: Crystal structure of mutant beta-K167T tryptophan synthase in complex with inhibitor N-(4'-trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) at the alpha-site, cesium ion at the metal coordination site, and 2-aminophenol quinonoid (1D0) at the beta-site
Class: lyase/lyase inhibitor
Keywords: F9F, 1D0, Cesium ion, mutant beta-K167T, lyase, lyase inhibitor, 2-aminophenol quinonoid, Salmonella typhimurium, LYASE-LYASE INHIBITOR complex
Deposited on
2018-06-20, released
2019-06-26
The last revision prior to the SCOPe 2.08 freeze date was dated
2019-12-18, with a file datestamp of
2019-12-13.
Experiment type: XRAY
Resolution: 1.79 Å
R-factor: N/A
AEROSPACI score: 0.37
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: tryptophan synthase alpha chain
Species: Salmonella typhimurium [TaxId:90371]
Gene: trpA, DD95_04145
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d6duca_ - Chain 'B':
Compound: tryptophan synthase beta chain
Species: Salmonella typhimurium [TaxId:90371]
Gene: trpB, DD95_04150
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d6ducb_ - Heterogens: F9F, DMS, EDO, CL, 1D0, 2AP, CS, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>6ducA (A:)
meryenlfaqlndrregafvpfvtlgdpgieqslkiidtlidagadalelgvpfsdplad
gptiqnanlrafaagvtpaqcfemlalirekhptipigllmyanlvfnngidafyarceq
vgvdsvlvadvpveesapfrqaalrhniapificppnadddllrqvasygrgytyllsrs
gvtgaenrgalplhhlieklkeyhaapalqgfgisspeqvsaavragaagaisgsaivki
ieknlaspkqmlaelrsfvsamkaasra
Sequence, based on observed residues (ATOM records): (download)
>6ducA (A:)
meryenlfaqlndrregafvpfvtlgdpgieqslkiidtlidagadalelgvpfsdplad
gptiqnanlrafaagvtpaqcfemlalirekhptipigllmyanlvfnngidafyarceq
vgvdsvlvadvpveesapfrqaalrhniapificppnadddllrqvasygrgytyllsrs
gvtgaenrplhhlieklkeyhaapalqgfgisspeqvsaavragaagaisgsaivkiiek
nlaspkqmlaelrsfvsamkaasra
- Chain 'B':
Sequence, based on SEQRES records: (download)
>6ducB (B:)
mttllnpyfgefggmyvpqilmpalnqleeafvsaqkdpefqaqfadllknyagrptalt
kcqnitagtrttlylkredllhggahktnqvlgqallakrmgkseiiaetgagqhgvasa
lasallglkcriymgakdverqspnvfrmrlmgaevipvhsgsatltdacnealrdwsgs
yetahymlgtaagphpyptivrefqrmigeetkaqildkegrlpdaviacvgggsnaigm
fadfindtsvgligvepgghgietgehgaplkhgrvgiyfgmkapmmqtadgqieesysi
sagldfpsvgpqhaylnsigradyvsitddealeafktlcrhegiipalesshalahalk
mmreqpekeqllvvnlsgrgdkdiftvhdilkargei
Sequence, based on observed residues (ATOM records): (download)
>6ducB (B:)
ttllnpyfgefggmyvpqilmpalnqleeafvsaqkdpefqaqfadllknyagrptaltk
cqnitagtrttlylkredllhggahktnqvlgqallakrmgkseiiaetgagqhgvasal
asallglkcriymgakdverqspnvfrmrlmgaevipvhsgsatltdacnealrdwsgsy
etahymlgtaagphpyptivrefqrmigeetkaqildkegrlpdaviacvgggsnaigmf
adfindtsvgligvepgghgietgehgaplkhgrvgiyfgmkapmmqtadgqieesysis
agldfpsvgpqhaylnsigradyvsitddealeafktlcrhegiipalesshalahalkm
mreqpekeqllvvnlsgrgdkdiftvhdilkarge