PDB entry 6db3

View 6db3 on RCSB PDB site
Description: JAK3 with Cyanamide CP23
Class: transferase/inhibitor
Keywords: kinase, TRANSFERASE-INHIBITOR complex
Deposited on 2018-05-02, released 2018-11-28
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-05-01, with a file datestamp of 2019-04-26.
Experiment type: XRAY
Resolution: 1.97 Å
R-factor: N/A
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Tyrosine-protein kinase JAK3
    Species: Homo sapiens [TaxId:9606]
    Gene: JAK3
    Database cross-references and differences (RAF-indexed):
    • Uniprot P52333
      • engineered mutation (244)
    Domains in SCOPe 2.08: d6db3a_
  • Heterogens: G54, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6db3A (A:)
mghhhhhhqdptifeerhlkyisqlgkgnfgsvelcrydplgdntgalvavkqlqhsgpd
qqrdfqreiqilkalhsdfivkyrgvsygpgrqslrlvmeylpsgclrdflqrhrarlda
srlllyssqickgmeylgsrrcvhrdlaarnilveseahvkiadfglakllpldkdyyvv
repgqspifwyapeslsdnifsrqsdvwsfgvvlyelftycdkscspsaeflrmmgcerd
vpalsrllelleegqrlpappacpaevhelmklcwapspqdrpsfsalgpqldmlwsgsr
gcethaftahpegkhhslsfs

    Sequence, based on observed residues (ATOM records): (download) 
    >6db3A (A:)
ptifeerhlkyisqlgkgnfgsvelcrydplgdntgalvavkqlqdqqrdfqreiqilka
lhsdfivkyrgvsygslrlvmeylpsgclrdflqrhrarldasrlllyssqickgmeylg
srrcvhrdlaarnilveseahvkiadfglakllpldkdyyvvrepgqspifwyapeslsd
nifsrqsdvwsfgvvlyelftycdkscspsaeflrmmdvpalsrllelleegqrlpappa
cpaevhelmklcwapspqdrpsfsalgpqldmlws