PDB entry 6c9j
View 6c9j on RCSB PDB site
Description: AMP-activated protein kinase bound to pharmacological activator R734
Class: transferase
Keywords: AMPK, activator, TRANSFERASE
Deposited on
2018-01-26, released
2018-11-28
The last revision prior to the SCOPe 2.08 freeze date was dated
2019-12-18, with a file datestamp of
2019-12-13.
Experiment type: XRAY
Resolution: 3.05 Å
R-factor: N/A
AEROSPACI score: 0.15
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: 5'-amp-activated protein kinase catalytic subunit alpha-1
Species: Homo sapiens [TaxId:9606]
Gene: Prkaa1, Ampk1
Database cross-references and differences (RAF-indexed):
- Chain 'B':
Compound: 5'-AMP-activated protein kinase subunit beta-1
Species: Homo sapiens [TaxId:9606]
Gene: PRKAB1, AMPK
Database cross-references and differences (RAF-indexed):
- Chain 'C':
Compound: 5'-amp-activated protein kinase subunit gamma-1
Species: Homo sapiens [TaxId:9606]
Gene: Prkag1
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d6c9jc1, d6c9jc2 - Heterogens: R34, STU, AMP
PDB Chain Sequences:
- Chain 'A':
No sequence available.
- Chain 'B':
No sequence available.
- Chain 'C':
Sequence, based on SEQRES records: (download)
>6c9jC (C:)
metvissdsspavenehpqetpesnnsvytsfmkshrcydliptssklvvfdtslqvkka
ffalvtngvraaplwdskkqsfvgmltitdfinilhryyksalvqiyeleehkietwrev
ylqdsfkplvcispnaslfdavsslirnkihrlpvidpesgntlyilthkrilkflklfi
tefpkpefmsksleelqigtyaniamvrtttpvyvalgifvqhrvsalpvvdekgrvvdi
yskfdvinlaaektynnldvsvtkalqhrshyfegvlkcylhetletiinrlveaevhrl
vvvdendvvkgivslsdilqalvlt
Sequence, based on observed residues (ATOM records): (download)
>6c9jC (C:)
nsvytsfmkshrcydliptssklvvfdtslqvkkaffalvtngvraaplwdskkqsfvgm
ltitdfinilhryyksalvqiyeleehkietwrevylqdsfkplvcispnaslfdavssl
irnkihrlpvidpesgntlyilthkrilkflklfitefpkpefmsksleelqigtyania
mvrtttpvyvalgifvqhrvsalpvvdekgrvvdiyskfdvinlaaektynnldvsvtka
lqhrshyfegvlkcylhetletiinrlveaevhrlvvvdendvvkgivslsdilqalvlt