PDB entry 6c98

View 6c98 on RCSB PDB site
Description: Crystal structure of FcRn bound to UCB-84
Class: immune system
Keywords: Neonatal Fc Receptor, FcRn, Inhibitor, beta 2 microglobulin, b2m, IMMUNE SYSTEM
Deposited on 2018-01-25, released 2018-05-30
The last revision prior to the SCOPe 2.07 freeze date was dated 2018-05-30, with a file datestamp of 2018-05-25.
Experiment type: XRAY
Resolution: 1.85 Å
R-factor: N/A
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: igg receptor fcrn large subunit p51
    Species: Homo sapiens [TaxId:9606]
    Gene: FCGRT, FCRN
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6c98a1, d6c98a2
  • Chain 'B':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M, CDABP0092, HDCMA22P
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6c98b_
  • Chain 'C':
    Compound: igg receptor fcrn large subunit p51
    Species: Homo sapiens [TaxId:9606]
    Gene: FCGRT, FCRN
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6c98c1, d6c98c2
  • Chain 'D':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M, CDABP0092, HDCMA22P
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6c98d_
  • Heterogens: CYS, ER7, GOL, PEG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >6c98A (A:)
    aeshlsllyhltavsspapgtpafwvsgwlgpqqylsynslrgeaepcgawvwenqvswy
    wekettdlrikeklfleafkalggkgpytlqgllgcelgpdntsvptakfalngeefmnf
    dlkqgtwggdwpealaisqrwqqqdkaankeltfllfscphrlrehlergrgnlewkepp
    smrlkarpsspgfsvltcsafsfyppelqlrflrnglaagtgqgdfgpnsdgsfhasssl
    tvksgdehhyccivqhaglaqplrvelespakss
    

    Sequence, based on observed residues (ATOM records): (download)
    >6c98A (A:)
    hlsllyhltavsspapgtpafwvsgwlgpqqylsynslrgeaepcgawvwenqvswywek
    ettdlrikeklfleafkalggpytlqgllgcelgpdntsvptakfalngeefmnfdlkqg
    twggdwpealaisqrwqqqdkaankeltfllfscphrlrehlergrgnlewkeppsmrlk
    arpsspgfsvltcsafsfyppelqlrflrnglaagtgqgdfgpnsdgsfhasssltvksg
    dehhyccivqhaglaqplrvel
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >6c98B (B:)
    iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdw
    sfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >6c98C (C:)
    aeshlsllyhltavsspapgtpafwvsgwlgpqqylsynslrgeaepcgawvwenqvswy
    wekettdlrikeklfleafkalggkgpytlqgllgcelgpdntsvptakfalngeefmnf
    dlkqgtwggdwpealaisqrwqqqdkaankeltfllfscphrlrehlergrgnlewkepp
    smrlkarpsspgfsvltcsafsfyppelqlrflrnglaagtgqgdfgpnsdgsfhasssl
    tvksgdehhyccivqhaglaqplrvelespakss
    

    Sequence, based on observed residues (ATOM records): (download)
    >6c98C (C:)
    hlsllyhltavsspapgtpafwvsgwlgpqqylsynslrgeaepcgawvwenqvswywek
    ettdlrikeklfleafkalggpytlqgllgcelgpdntsvptakfalngeefmnfdlkqg
    twggdwpealaisqrwqqqdkaankeltfllfscphrlrehlergrgnlewkeppsmrlk
    arpsspgfsvltcsafsfyppelqlrflrnglaagtgqgdfgpnsdgsfhasssltvksg
    dehhyccivqhaglaqplrvel
    

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download)
    >6c98D (D:)
    iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdw
    sfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm