PDB entry 6c3k

View 6c3k on RCSB PDB site
Description: Apo crystal structure of S. aureus penicillin binding protein 4 (PBP4) mutant (E183A, F241R)
Class: hydrolase
Keywords: Hydrolase, Penicillin binding protein
Deposited on 2018-01-10, released 2018-11-07
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-01-08, with a file datestamp of 2020-01-03.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: N/A
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Penicillin-binding protein 4
    Species: Staphylococcus aureus (strain COL) [TaxId:93062]
    Gene: pbp4, SACOL0699
    Database cross-references and differences (RAF-indexed):
    • Uniprot A0A0H2WY27 (Start-366)
      • engineered mutation (166)
      • engineered mutation (224)
    Domains in SCOPe 2.08: d6c3ka1, d6c3ka2
  • Chain 'B':
    Compound: Penicillin-binding protein 4
    Species: Staphylococcus aureus (strain COL) [TaxId:93062]
    Gene: pbp4, SACOL0699
    Database cross-references and differences (RAF-indexed):
    • Uniprot A0A0H2WY27 (Start-366)
      • engineered mutation (166)
      • engineered mutation (224)
    Domains in SCOPe 2.08: d6c3kb1, d6c3kb2
  • Heterogens: ZN, NA, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6c3kA (A:)
gshmyaqatnsdvtpvqaanqygyaglsaayeptsavnvsqtgqllyqynidtkwnpasm
tklmtmyltleavnkgqlslddtvtmtnkeyimstlpelsntklypgqvwtiadllqitv
snssnaaalilakkvskntsdfvdlmnnkakaigmknthfvnptgaansrlrtfaptkyk
dqertvttardyaildlhviketpkildftkqlaptthavtyytrnfslegakmslpgtd
glktgssdtanynhtittkrgkfrinqvimgagdyknlggekqrnmmgnalmersfdqyk
yvkilskgeqringkkyyvendlydvlpsdfskkdyklvvedgkvhadyprefinkdygp
ptvevhq

    Sequence, based on observed residues (ATOM records): (download) 
    >6c3kA (A:)
tnsdvtpvqaanqygyaglsaayeptsavnvsqtgqllyqynidtkwnpasmtklmtmyl
tleavnkgqlslddtvtmtnkeyimstlpelsntklypgqvwtiadllqitvsnssnaaa
lilakkvskntsdfvdlmnnkakaigmknthfvnptgaansrlrtfaptkykdqertvtt
ardyaildlhviketpkildftkqlaptthavtyytrnfslegakmslpgtdglktgssd
tanynhtittkrgkfrinqvimgagdyknlggekqrnmmgnalmersfdqykyvkilskg
eqringkkyyvendlydvlpsdfskkdyklvvedgkvhadyprefinkdygpptvevhq

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6c3kB (B:)
gshmyaqatnsdvtpvqaanqygyaglsaayeptsavnvsqtgqllyqynidtkwnpasm
tklmtmyltleavnkgqlslddtvtmtnkeyimstlpelsntklypgqvwtiadllqitv
snssnaaalilakkvskntsdfvdlmnnkakaigmknthfvnptgaansrlrtfaptkyk
dqertvttardyaildlhviketpkildftkqlaptthavtyytrnfslegakmslpgtd
glktgssdtanynhtittkrgkfrinqvimgagdyknlggekqrnmmgnalmersfdqyk
yvkilskgeqringkkyyvendlydvlpsdfskkdyklvvedgkvhadyprefinkdygp
ptvevhq

    Sequence, based on observed residues (ATOM records): (download) 
    >6c3kB (B:)
tnsdvtpvqaanqygyaglsaayeptsavnvsqtgqllyqynidtkwnpasmtklmtmyl
tleavnkgqlslddtvtmtnkeyimstlpelsntklypgqvwtiadllqitvsnssnaaa
lilakkvskntsdfvdlmnnkakaigmknthfvnptgaansrlrtfaptkykdqertvtt
ardyaildlhviketpkildftkqlaptthavtyytrnfslegakmslpgtdglktgssd
tanynhtittkrgkfrinqvimgagdykggekqrnmmgnalmersfdqykyvkilskgeq
ringkkyyvendlydvlpsdfskkdyklvvedgkvhadyprefinkdygpptvevhq