PDB entry 6c09

View 6c09 on RCSB PDB site
Description: Ternary crystal structure of the 3C8 TCR-CD1c-monoacylglycerol complex
Class: immune system
Keywords: T cell Receptor, Antigen Presentation, IMMUNE SYSTEM
Deposited on 2017-12-28, released 2018-03-21
The last revision prior to the SCOPe 2.07 freeze date was dated 2018-04-04, with a file datestamp of 2018-03-29.
Experiment type: XRAY
Resolution: 2.95 Å
R-factor: N/A
AEROSPACI score: 0.14 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: T-cell surface glycoprotein CD1c
    Species: Homo sapiens [TaxId:9606]
    Gene: CD1C
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6c09a1, d6c09a2
  • Chain 'B':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M, CDABP0092, HDCMA22P
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6c09b_
  • Chain 'C':
    Compound: 3C8 T cell receptor alpha-chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6C09
    Domains in SCOPe 2.07: d6c09c1, d6c09c2
  • Chain 'D':
    Compound: 3C8 T cell receptor beta-chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6C09
    Domains in SCOPe 2.07: d6c09d1, d6c09d2
  • Heterogens: NAG, EKG, D10, K, EDO, PEG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >6c09A (A:)
    etgadasqehvsfhviqifsfvnqswargqgsgwldelqthgwdsesgtiiflhnwskgn
    fsneelsdlellfrfylfgltreiqdhasqdyskypfevqvkagcelhsgkspegffqva
    fngldllsfqnttwvpspgcgslaqsvchllnhqyegvtetvynlirstcprfllgllda
    gkmyvhrqvrpeawlssrpslgsgqlllvchasgfypkpvwvtwmrneqeqlgtkhgdil
    pnadgtwylqvilevaseepaglscrvrhsslggqdiilywgslvpr
    

    Sequence, based on observed residues (ATOM records): (download)
    >6c09A (A:)
    hvsfhviqifsfvnqswargqgsgwldelqthgwdsesgtiiflhnwskgnfsneelsdl
    ellfrfylfgltreiqdhasqdyskypfevqvkagcelhsgkspegffqvafngldllsf
    qnttwvpspgcgslaqsvchllnhqyegvtetvynlirstcprfllglldagkmyvhrqv
    rpeawlssrpslgqlllvchasgfypkpvwvtwmrneqeqlgtkhgdilpnadgtwylqv
    ilevaseaglscrvrhsslggqdiilywg
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >6c09B (B:)
    etgiqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfs
    kdwsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdmgslvpr
    

    Sequence, based on observed residues (ATOM records): (download)
    >6c09B (B:)
    qrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdws
    fyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >6c09C (C:)
    mdqqvkqnspslsvqegrisilncdytnsmfdyflwykkypaegptflisissikdkned
    grftvflnksakhlslhivpsqpgdsavyfcaasvgdkiifgkgtrlhilpnmqnpdpav
    yqlrdskssdksvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsavawsnks
    dfacanafnnsiipedtffpspess
    

    Sequence, based on observed residues (ATOM records): (download)
    >6c09C (C:)
    qqvkqnspslsvqegrisilncdytnsmfdyflwykkypaegptflisissikdknedgr
    ftvflnksakhlslhivpsqpgdsavyfcaasvgdkiifgkgtrlhilpnmqnpdpavyq
    lrdskssdksvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsavawsacana
    fnnsiipedtff
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >6c09D (D:)
    mgagvsqspsnkvtekgkdvelrcdpisghtalywyrqslgqglefliyfqgnsapdksg
    lpsdrfsaertggsvstltiqrtqqedsavylcasssyrgprmneqffgpgtrltvledl
    knvfppevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqpl
    keqpalndsryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsa
    eawgrad
    

    Sequence, based on observed residues (ATOM records): (download)
    >6c09D (D:)
    agvsqspsnkvtekgkdvelrcdpisghtalywyrqslgqglefliyfqgnsapdksglp
    sdrfsaertggsvstltiqrtqqedsavylcasssyrgprmneqffgpgtrltvledlkn
    vfppevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplke
    qpalndsryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsaea
    wgra