PDB entry 6bbv

View 6bbv on RCSB PDB site
Description: Crystal Structure of JAK2 in complex with compound 25
Class: transferase/transferase inhibitor
Keywords: Kinase, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2017-10-19, released 2018-01-17
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-02-28, with a file datestamp of 2018-02-23.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: N/A
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Tyrosine-protein kinase JAK2
    Species: Homo sapiens [TaxId:9606]
    Gene: JAK2
    Database cross-references and differences (RAF-indexed):
    • Uniprot O60674
      • conflict (238)
      • conflict (241)
    Domains in SCOPe 2.08: d6bbva_
  • Heterogens: D7D, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6bbvA (A:)
gsedrdptqfeerhlkflqqlgkgnfgsvemcrydplqdntgevvavkklqhsteehlrd
fereieilkslqhdnivkykgvcysagrrnlklimeylpygslrdylqkhkeridhikll
qytsqickgmeylgtkryihrdlatrnilvenenrvkigdfgltkvlpqdkeyykvkepg
espifwyapeslteskfsvasdvwsfgvvlyelftyieksksppaefmrmigndkqgqsi
vthliellknngrlprpdgcpdeiymimtecwnnnvnqrpsfrdlalrvdqirdnmag

    Sequence, based on observed residues (ATOM records): (download) 
    >6bbvA (A:)
qfeerhlkflqqlgkgnfgsvemcrydplqdntgevvavkklqhsteehlrdfereieil
kslqhdnivkykgvcysagrrnlklimeylpygslrdylqkhkeridhikllqytsqick
gmeylgtkryihrdlatrnilvenenrvkigdfgltkvlpqdkeyykvkepgespifwya
peslteskfsvasdvwsfgvvlyelftyieksksppaefmrmigndkqgqsivthliell
knngrlprpdgcpdeiymimtecwnnnvnqrpsfrdlalrvdqirdnma