PDB entry 6b8q

View 6b8q on RCSB PDB site
Description: Crystal Structure of the Mg2+/CaM:Kv7.5 (KCNQ5) AB domain complex
Class: metal transport
Keywords: ion channel, complex, METAL TRANSPORT
Deposited on 2017-10-09, released 2018-03-14
The last revision prior to the SCOPe 2.07 freeze date was dated 2018-03-14, with a file datestamp of 2018-03-09.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: N/A
AEROSPACI score: 0.19 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Potassium voltage-gated channel subfamily KQT member 5
    Species: Homo sapiens [TaxId:9606]
    Gene: KCNQ5
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9NR82 (Start-38)
      • linker (39)
    • Uniprot Q9NR82 (40-End)
      • linker (40)
  • Chain 'B':
    Compound: Calmodulin-1
    Species: Homo sapiens [TaxId:9606]
    Gene: Calm1, Calm, Cam, Cam1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6b8qb_
  • Chain 'C':
    Compound: Potassium voltage-gated channel subfamily KQT member 5
    Species: Homo sapiens [TaxId:9606]
    Gene: KCNQ5
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9NR82 (Start-38)
      • linker (39)
    • Uniprot Q9NR82 (40-End)
      • linker (40)
  • Chain 'D':
    Compound: Calmodulin-1
    Species: Homo sapiens [TaxId:9606]
    Gene: Calm1, Calm, Cam, Cam1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6b8qd_
  • Chain 'E':
    Compound: Potassium voltage-gated channel subfamily KQT member 5
    Species: Homo sapiens [TaxId:9606]
    Gene: KCNQ5
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9NR82 (Start-38)
      • linker (39)
    • Uniprot Q9NR82 (40-End)
      • linker (40)
  • Chain 'F':
    Compound: Calmodulin-1
    Species: Homo sapiens [TaxId:9606]
    Gene: Calm1, Calm, Cam, Cam1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6b8qf_
  • Chain 'G':
    Compound: Potassium voltage-gated channel subfamily KQT member 5
    Species: Homo sapiens [TaxId:9606]
    Gene: KCNQ5
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9NR82 (5-38)
      • linker (39)
    • Uniprot Q9NR82 (40-End)
      • linker (40)
  • Chain 'H':
    Compound: Calmodulin-1
    Species: Homo sapiens [TaxId:9606]
    Gene: Calm1, Calm, Cam, Cam1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6b8qh_
  • Heterogens: MG, HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >6b8qB (B:)
    madqlteeqiaefkeafslfdkdgdgtittkelgtvmrslgqnpteaelqdminevdadg
    ngtidfpefltmmarkmkdtdseeeireafrvfdkdgngyisaaelrhvmtnlgekltde
    evdemireadidgdgqvnyeefvqmmtak
    

    Sequence, based on observed residues (ATOM records): (download)
    >6b8qB (B:)
    dqlteeqiaefkeafslfdkdgdgtittkelgtvmrslgqnpteaelqdminevdadgng
    tidfpefltmmarkmkdtdseeeireafrvfdkdgngyisaaelrhvmtnlgekltdeev
    demireadidgdgqvnyeefvqmmta
    

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >6b8qD (D:)
    madqlteeqiaefkeafslfdkdgdgtittkelgtvmrslgqnpteaelqdminevdadg
    ngtidfpefltmmarkmkdtdseeeireafrvfdkdgngyisaaelrhvmtnlgekltde
    evdemireadidgdgqvnyeefvqmmtak
    

    Sequence, based on observed residues (ATOM records): (download)
    >6b8qD (D:)
    teeqiaefkeafslfdkdgdgtittkelgtvmrslgqnpteaelqdminevdadgngtid
    fpefltmmarkmkdtdseeeireafrvfdkdgngyisaaelrhvmtnlgekltdeevdem
    ireadidgdgqvnyeefvqmmta
    

  • Chain 'E':
    No sequence available.

  • Chain 'F':
    Sequence, based on SEQRES records: (download)
    >6b8qF (F:)
    madqlteeqiaefkeafslfdkdgdgtittkelgtvmrslgqnpteaelqdminevdadg
    ngtidfpefltmmarkmkdtdseeeireafrvfdkdgngyisaaelrhvmtnlgekltde
    evdemireadidgdgqvnyeefvqmmtak
    

    Sequence, based on observed residues (ATOM records): (download)
    >6b8qF (F:)
    lteeqiaefkeafslfdkdgdgtittkelgtvmrslgqnpteaelqdminevdadgngti
    dfpefltmmarkmkdtdseeeireafrvfdkdgngyisaaelrhvmtnlgekltdeevde
    mireadidgdgqvnyeefvqmmta
    

  • Chain 'G':
    No sequence available.

  • Chain 'H':
    Sequence, based on SEQRES records: (download)
    >6b8qH (H:)
    madqlteeqiaefkeafslfdkdgdgtittkelgtvmrslgqnpteaelqdminevdadg
    ngtidfpefltmmarkmkdtdseeeireafrvfdkdgngyisaaelrhvmtnlgekltde
    evdemireadidgdgqvnyeefvqmmtak
    

    Sequence, based on observed residues (ATOM records): (download)
    >6b8qH (H:)
    dqlteeqiaefkeafslfdkdgdgtittkelgtvmrslgqnpteaelqdminevdadgng
    tidfpefltmmarkmkdtdseeeireafrvfdkdgngyisaaelrhvmtnlgekltdeev
    demireadidgdgqvnyeefvqmmta