PDB entry 6ayt

View 6ayt on RCSB PDB site
Description: Crystal structure of Campylobacter jejuni 5'-methylthioadenosine/S-adenosyl homocysteine nucleosidase (MTAN) complexed with pyrazinylthio-DADMe-Immucillin-A
Class: hydrolase, transferase
Keywords: MTAN enzyme, Foodborne Diseases, HYDROLASE, TRANSFERASE
Deposited on 2017-09-08, released 2018-09-12
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-03-27, with a file datestamp of 2019-03-22.
Experiment type: XRAY
Resolution: 1.85 Å
R-factor: N/A
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase
    Species: Campylobacter jejuni [TaxId:197]
    Gene: A0M70_07260, AJY53_05400
    Database cross-references and differences (RAF-indexed):
    • Uniprot A0A1E7P7U4 (10-237)
      • expression tag (9)
      • conflict (49)
    Domains in SCOPe 2.08: d6ayta1, d6ayta2
  • Chain 'B':
    Compound: 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase
    Species: Campylobacter jejuni [TaxId:197]
    Gene: A0M70_07260, AJY53_05400
    Database cross-references and differences (RAF-indexed):
    • Uniprot A0A1E7P7U4 (10-237)
      • expression tag (9)
      • conflict (49)
    Domains in SCOPe 2.08: d6aytb1, d6aytb2
  • Chain 'C':
    Compound: 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase
    Species: Campylobacter jejuni [TaxId:197]
    Gene: A0M70_07260, AJY53_05400
    Database cross-references and differences (RAF-indexed):
    • Uniprot A0A1E7P7U4 (10-237)
      • expression tag (9)
      • conflict (49)
    Domains in SCOPe 2.08: d6aytc1, d6aytc2
  • Chain 'D':
    Compound: 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase
    Species: Campylobacter jejuni [TaxId:197]
    Gene: A0M70_07260, AJY53_05400
    Database cross-references and differences (RAF-indexed):
    • Uniprot A0A1E7P7U4 (10-237)
      • expression tag (9)
      • conflict (49)
    Domains in SCOPe 2.08: d6aytd1, d6aytd2
  • Heterogens: 4EH, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6aytA (A:)
mghhhhhhsgmkiailgamseeitplletlkdytkiehanntyyfakykdhelvlayski
gkvnstlsasvmiekfgaqvllftgvagafnpeleigdllyatklaqydlditafghplg
fvpgneifiktdeklnnlalevakelniklragiiatgdeficdeakkakireifnadac
emegasvalvcdalkvpcfilramsdkagekaefdfdefvinsakisanfvlkmcekl

    Sequence, based on observed residues (ATOM records): (download) 
    >6aytA (A:)
gmkiailgamseeitplletlkdytkiehanntyyfakykdhelvlayskigkvnstlsa
svmiekfgaqvllftgvagafnpeleigdllyatklaqydlditafghplgfvpgneifi
ktdeklnnlalevakelniklragiiatgdeficdeakkakireifnadacemegasval
vcdalkvpcfilramsdkagekaefdfdefvinsakisanfvlkmcekl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6aytB (B:)
mghhhhhhsgmkiailgamseeitplletlkdytkiehanntyyfakykdhelvlayski
gkvnstlsasvmiekfgaqvllftgvagafnpeleigdllyatklaqydlditafghplg
fvpgneifiktdeklnnlalevakelniklragiiatgdeficdeakkakireifnadac
emegasvalvcdalkvpcfilramsdkagekaefdfdefvinsakisanfvlkmcekl

    Sequence, based on observed residues (ATOM records): (download) 
    >6aytB (B:)
gmkiailgamseeitplletlkdytkiehanntyyfakykdhelvlayskigkvnstlsa
svmiekfgaqvllftgvagafnpeleigdllyatklaqydlditafghplgfvpgneifi
ktdeklnnlalevakelniklragiiatgdeficdeakkakireifnadacemegasval
vcdalkvpcfilramsdkagekaefdfdefvinsakisanfvlkmcekl

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6aytC (C:)
mghhhhhhsgmkiailgamseeitplletlkdytkiehanntyyfakykdhelvlayski
gkvnstlsasvmiekfgaqvllftgvagafnpeleigdllyatklaqydlditafghplg
fvpgneifiktdeklnnlalevakelniklragiiatgdeficdeakkakireifnadac
emegasvalvcdalkvpcfilramsdkagekaefdfdefvinsakisanfvlkmcekl

    Sequence, based on observed residues (ATOM records): (download) 
    >6aytC (C:)
gmkiailgamseeitplletlkdytkiehanntyyfakykdhelvlayskigkvnstlsa
svmiekfgaqvllftgvagafnpeleigdllyatklaqydlditafghplgfvpgneifi
ktdeklnnlalevakelniklragiiatgdeficdeakkakireifnadacemegasval
vcdalkvpcfilramsdkagekaefdfdefvinsakisanfvlkmcekl

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6aytD (D:)
mghhhhhhsgmkiailgamseeitplletlkdytkiehanntyyfakykdhelvlayski
gkvnstlsasvmiekfgaqvllftgvagafnpeleigdllyatklaqydlditafghplg
fvpgneifiktdeklnnlalevakelniklragiiatgdeficdeakkakireifnadac
emegasvalvcdalkvpcfilramsdkagekaefdfdefvinsakisanfvlkmcekl

    Sequence, based on observed residues (ATOM records): (download) 
    >6aytD (D:)
gmkiailgamseeitplletlkdytkiehanntyyfakykdhelvlayskigkvnstlsa
svmiekfgaqvllftgvagafnpeleigdllyatklaqydlditafghplgfvpgneifi
ktdeklnnlalevakelniklragiiatgdeficdeakkakireifnadacemegasval
vcdalkvpcfilramsdkagekaefdfdefvinsakisanfvlkmcekl