PDB entry 6a6i

View 6a6i on RCSB PDB site
Description: Crystal structure of the winged-helix domain of Cockayne syndrome group B protein in complex with ubiquitin
Class: hydrolase
Keywords: DNA repair, helicase, ubiquitin, molecular signaling, HYDROLASE
Deposited on 2018-06-28, released 2019-02-13
The last revision prior to the SCOPe 2.07 freeze date was dated 2019-02-13, with a file datestamp of 2019-02-08.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: N/A
AEROSPACI score: 0.22 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Excision repair cross-complementing rodent repair deficiency, complementation group 6 variant
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q59FF6 (5-97)
      • expression tag (4)
  • Chain 'B':
    Compound: Polyubiquitin-B
    Species: Homo sapiens [TaxId:9606]
    Gene: UBB
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0CG47 (0-End)
      • engineered mutation (47)
    Domains in SCOPe 2.07: d6a6ib_
  • Chain 'C':
    Compound: Excision repair cross-complementing rodent repair deficiency, complementation group 6 variant
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q59FF6 (5-97)
      • expression tag (4)
  • Chain 'D':
    Compound: Polyubiquitin-B
    Species: Homo sapiens [TaxId:9606]
    Gene: UBB
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0CG47 (0-75)
      • engineered mutation (47)
    Domains in SCOPe 2.07: d6a6id_
  • Chain 'E':
    Compound: Excision repair cross-complementing rodent repair deficiency, complementation group 6 variant
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q59FF6 (5-97)
      • expression tag (4)
  • Chain 'F':
    Compound: Polyubiquitin-B
    Species: Homo sapiens [TaxId:9606]
    Gene: UBB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6a6if_
  • Chain 'G':
    Compound: Excision repair cross-complementing rodent repair deficiency, complementation group 6 variant
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'H':
    Compound: Polyubiquitin-B
    Species: Homo sapiens [TaxId:9606]
    Gene: UBB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6a6ih_
  • Heterogens: GOL, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >6a6iB (B:)
    mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagrqledgrtlsdyn
    iqkestlhlvlrlrgg
    

    Sequence, based on observed residues (ATOM records): (download)
    >6a6iB (B:)
    mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagrqledgrtlsdyn
    iqkestlhlvlrlr
    

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download)
    >6a6iD (D:)
    mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagrqledgrtlsdyn
    iqkestlhlvlrlrgg
    

  • Chain 'E':
    No sequence available.

  • Chain 'F':
    Sequence, based on SEQRES records: (download)
    >6a6iF (F:)
    mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
    iqkestlhlvlrlrggd
    

    Sequence, based on observed residues (ATOM records): (download)
    >6a6iF (F:)
    mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
    iqkestlhlvlrlr
    

  • Chain 'G':
    No sequence available.

  • Chain 'H':
    Sequence, based on SEQRES records: (download)
    >6a6iH (H:)
    mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
    iqkestlhlvlrlrggd
    

    Sequence, based on observed residues (ATOM records): (download)
    >6a6iH (H:)
    mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
    iqkestlhlvlrlr