PDB entry 5zo9

View 5zo9 on RCSB PDB site
Description: Eg5 motor domain in complex with STLC-type inhibitor PVEI0021 (C2 type)
Class: cell cycle
Keywords: motor domain ATP binding, CELL CYCLE
Deposited on 2018-04-12, released 2018-10-10
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-09-11, with a file datestamp of 2019-09-06.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: N/A
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Kinesin-like protein KIF11
    Species: Homo sapiens [TaxId:9606]
    Gene: KIF11, EG5, KNSL1, TRIP5
    Database cross-references and differences (RAF-indexed):
    • Uniprot P52732 (7-End)
      • expression tag (6)
    Domains in SCOPe 2.08: d5zo9a1, d5zo9a2
  • Chain 'B':
    Compound: Kinesin-like protein KIF11
    Species: Homo sapiens [TaxId:9606]
    Gene: KIF11, EG5, KNSL1, TRIP5
    Database cross-references and differences (RAF-indexed):
    • Uniprot P52732 (7-End)
      • expression tag (6)
    Domains in SCOPe 2.08: d5zo9b1, d5zo9b2
  • Heterogens: ADP, MG, 4C5, SO4, NA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5zo9A (A:)
mnhkvhmkniqvvvrcrpfnlaerkasahsivecdpvrkevsvrtggladkssrktytfd
mvfgastkqidvyrsvvcpildevimgynctifaygqtgtgktftmegerspneeytwee
dplagiiprtlhqifekltdngtefsvkvslleiyneelfdllnpssdvserlqmfddpr
nkrgviikgleeitvhnkdevyqilekgaakrttaatlmnayssrshsvfsvtihmkett
idgeelvkigklnlvdlagsenigrsgavdkrareagninqslltlgrvitalvertphv
pyreskltrilqdslggrtrtsiiatispaslnleetlstleyahraknilnkpevnqkl
qhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >5zo9A (A:)
mkniqvvvrcrpfnlaerkasahsivecdpvrkevsvrtssrktytfdmvfgastkqidv
yrsvvcpildevimgynctifaygqtgtgktftmegerspneeytweedplagiiprtlh
qifekltdngtefsvkvslleiyneelfdllnpssdvserlqmfddprnkrgviikglee
itvhnkdevyqilekgaakrttaatlmnayssrshsvfsvtihmkettidgeelvkigkl
nlvdlagsenninqslltlgrvitalvertphvpyreskltrilqdslggrtrtsiiati
spaslnleetlstleyahraknilnkpevnq

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5zo9B (B:)
mnhkvhmkniqvvvrcrpfnlaerkasahsivecdpvrkevsvrtggladkssrktytfd
mvfgastkqidvyrsvvcpildevimgynctifaygqtgtgktftmegerspneeytwee
dplagiiprtlhqifekltdngtefsvkvslleiyneelfdllnpssdvserlqmfddpr
nkrgviikgleeitvhnkdevyqilekgaakrttaatlmnayssrshsvfsvtihmkett
idgeelvkigklnlvdlagsenigrsgavdkrareagninqslltlgrvitalvertphv
pyreskltrilqdslggrtrtsiiatispaslnleetlstleyahraknilnkpevnqkl
qhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >5zo9B (B:)
mkniqvvvrcrpfnlaerkasahsivecdpvrkevsvrtssrktytfdmvfgastkqidv
yrsvvcpildevimgynctifaygqtgtgktftmegerspneeytweedplagiiprtlh
qifekltdngtefsvkvslleiyneelfdllnpssdvserlqmfddprnkrgviikglee
itvhnkdevyqilekgaakrttaatlmnayssrshsvfsvtihmkettidgeelvkigkl
nlvdlagsenninqslltlgrvitalvertphvpyreskltrilqdslggrtrtsiiati
spaslnleetlstleyahraknilnkpevnq