PDB entry 5z18

View 5z18 on RCSB PDB site
Description: The crystal structure of Ruminococcus gnavus beta-glucuronidase
Class: hydrolase
Keywords: beta-glucuronidase, GH2, HYDROLASE
Deposited on 2017-12-25, released 2018-12-12
The last revision prior to the SCOPe 2.07 freeze date was dated 2018-12-12, with a file datestamp of 2018-12-07.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: N/A
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: beta-glucuronidase
    Species: Ruminococcus gnavus [TaxId:33038]
    Gene: uidA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5z18a1, d5z18a2, d5z18a3
  • Chain 'B':
    Compound: beta-glucuronidase
    Species: Ruminococcus gnavus [TaxId:33038]
    Gene: uidA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5z18b1, d5z18b2, d5z18b3
  • Chain 'C':
    Compound: beta-glucuronidase
    Species: Ruminococcus gnavus [TaxId:33038]
    Gene: uidA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5z18c1, d5z18c2, d5z18c3
  • Chain 'D':
    Compound: beta-glucuronidase
    Species: Ruminococcus gnavus [TaxId:33038]
    Gene: uidA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5z18d1, d5z18d2, d5z18d3
  • Chain 'E':
    Compound: beta-glucuronidase
    Species: Ruminococcus gnavus [TaxId:33038]
    Gene: uidA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5z18e1, d5z18e2, d5z18e3
  • Chain 'F':
    Compound: beta-glucuronidase
    Species: Ruminococcus gnavus [TaxId:33038]
    Gene: uidA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5z18f1, d5z18f2, d5z18f3
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5z18A (A:)
mhhhhhhssgvdlgtenlyfqsngmleyselypiqneyrmmqsldgmwkfqfdpeeigkk
sgwenglpapvsmpvpssfadfftdhkerdycgdfwyetefylpaewrnkkiwlrfgsit
hrgtvycngmeitsheggflpvladistvakpgqvnqvvvkinnelnetslpcgatkiln
ngrklakpyfdffnysglqrsvwvialpeesvkdysvdyelcgtdalvkyevvttgehpv
ivrlldaegelvaetegkegilqvanarlwevrnaylyqivilitdgngvldeyrekigi
rtvriegtkillndrpvylkgfgkhedfpilgrgfhwgivkrdfeclkwtnancfrtshy
pyaeewyqfadeegfliidevpavgmmrstrnfvaagsgnytyffealtvpellkshiad
teemitrdknhpsviawslfnepetitdyayeyfkevfaaaetydfqsrpmtgafeknsk
pelckcyplcdficlnryygwyisggpeieeaeelfrdemdrwkakelnvpfvftefgtd
tmaglhklpsimwseeyqkeylemnfrvfdsyefvqgelawnfadfqttegimrvdgnhk
gvftrdrqpkaaavvfkdrwekknelf

    Sequence, based on observed residues (ATOM records): (download) 
    >5z18A (A:)
leyselypiqneyrmmqsldgmwkfqfdpeeigkksgwenglpapvsmpvpssfadfftd
hkerdycgdfwyetefylpaewrnkkiwlrfgsithrgtvycngmeitsheggflpvlad
istvakpgqvnqvvvkinnelnetslpcgatkilnngrklakpyfdffnysglqrsvwvi
alpeesvkdysvdyelcgtdalvkyevvttgehpvivrlldaegelvaetegkegilqva
narlwevrnaylyqivilitdgngvldeyrekigirtvriegtkillndrpvylkgfgkh
edfpilgrgfhwgivkrdfeclkwtnancfrtshypyaeewyqfadeegfliidevpavg
mmrstytyffealtvpellkshiadteemitrdknhpsviawslfnepetitdyayeyfk
evfaaaetydfqsrpmtgafeknskpelckcyplcdficlnryygwyisggpeieeaeel
frdemdrwkakelnvpfvftefgtdtmaglhklpsimwseeyqkeylemnfrvfdsyefv
qgelawnfadfqttegimrvdgnhkgvftrdrqpkaaavvfkdrwe

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5z18B (B:)
mhhhhhhssgvdlgtenlyfqsngmleyselypiqneyrmmqsldgmwkfqfdpeeigkk
sgwenglpapvsmpvpssfadfftdhkerdycgdfwyetefylpaewrnkkiwlrfgsit
hrgtvycngmeitsheggflpvladistvakpgqvnqvvvkinnelnetslpcgatkiln
ngrklakpyfdffnysglqrsvwvialpeesvkdysvdyelcgtdalvkyevvttgehpv
ivrlldaegelvaetegkegilqvanarlwevrnaylyqivilitdgngvldeyrekigi
rtvriegtkillndrpvylkgfgkhedfpilgrgfhwgivkrdfeclkwtnancfrtshy
pyaeewyqfadeegfliidevpavgmmrstrnfvaagsgnytyffealtvpellkshiad
teemitrdknhpsviawslfnepetitdyayeyfkevfaaaetydfqsrpmtgafeknsk
pelckcyplcdficlnryygwyisggpeieeaeelfrdemdrwkakelnvpfvftefgtd
tmaglhklpsimwseeyqkeylemnfrvfdsyefvqgelawnfadfqttegimrvdgnhk
gvftrdrqpkaaavvfkdrwekknelf

    Sequence, based on observed residues (ATOM records): (download) 
    >5z18B (B:)
leyselypiqneyrmmqsldgmwkfqfdpeeigkksgwenglpapvsmpvpssfadfftd
hkerdycgdfwyetefylpaewrnkkiwlrfgsithrgtvycngmeitsheggflpvlad
istvakpgqvnqvvvkinnelnetslpcgatkilnngrklakpyfdffnysglqrsvwvi
alpeesvkdysvdyelcgtdalvkyevvttgehpvivrlldaegelvaetegkegilqva
narlwevrnaylyqivilitdgngvldeyrekigirtvriegtkillndrpvylkgfgkh
edfpilgrgfhwgivkrdfeclkwtnancfrtshypyaeewyqfadeegfliidevpavg
mmrstytyffealtvpellkshiadteemitrdknhpsviawslfnepetitdyayeyfk
evfaaaetydfqsrpmtgafeknskpelckcyplcdficlnryygwyisggpeieeaeel
frdemdrwkakelnvpfvftefgtdtmaglhklpsimwseeyqkeylemnfrvfdsyefv
qgelawnfadfqttegimrvdgnhkgvftrdrqpkaaavvfkdrwe

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >5z18C (C:)
mhhhhhhssgvdlgtenlyfqsngmleyselypiqneyrmmqsldgmwkfqfdpeeigkk
sgwenglpapvsmpvpssfadfftdhkerdycgdfwyetefylpaewrnkkiwlrfgsit
hrgtvycngmeitsheggflpvladistvakpgqvnqvvvkinnelnetslpcgatkiln
ngrklakpyfdffnysglqrsvwvialpeesvkdysvdyelcgtdalvkyevvttgehpv
ivrlldaegelvaetegkegilqvanarlwevrnaylyqivilitdgngvldeyrekigi
rtvriegtkillndrpvylkgfgkhedfpilgrgfhwgivkrdfeclkwtnancfrtshy
pyaeewyqfadeegfliidevpavgmmrstrnfvaagsgnytyffealtvpellkshiad
teemitrdknhpsviawslfnepetitdyayeyfkevfaaaetydfqsrpmtgafeknsk
pelckcyplcdficlnryygwyisggpeieeaeelfrdemdrwkakelnvpfvftefgtd
tmaglhklpsimwseeyqkeylemnfrvfdsyefvqgelawnfadfqttegimrvdgnhk
gvftrdrqpkaaavvfkdrwekknelf

    Sequence, based on observed residues (ATOM records): (download) 
    >5z18C (C:)
leyselypiqneyrmmqsldgmwkfqfdpeeigkksgwenglpapvsmpvpssfadfftd
hkerdycgdfwyetefylpaewrnkkiwlrfgsithrgtvycngmeitsheggflpvlad
istvakpgqvnqvvvkinnelnetslpcgatkilnngrklakpyfdffnysglqrsvwvi
alpeesvkdysvdyelcgtdalvkyevvttgehpvivrlldaegelvaetegkegilqva
narlwevrnaylyqivilitdgngvldeyrekigirtvriegtkillndrpvylkgfgkh
edfpilgrgfhwgivkrdfeclkwtnancfrtshypyaeewyqfadeegfliidevpavg
mmrstytyffealtvpellkshiadteemitrdknhpsviawslfnepetitdyayeyfk
evfaaaetydfqsrpmtgafeknskpelckcyplcdficlnryygwyisggpeieeaeel
frdemdrwkakelnvpfvftefgtdtmaglhklpsimwseeyqkeylemnfrvfdsyefv
qgelawnfadfqttegimrvdgnhkgvftrdrqpkaaavvfkdrwekk

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >5z18D (D:)
mhhhhhhssgvdlgtenlyfqsngmleyselypiqneyrmmqsldgmwkfqfdpeeigkk
sgwenglpapvsmpvpssfadfftdhkerdycgdfwyetefylpaewrnkkiwlrfgsit
hrgtvycngmeitsheggflpvladistvakpgqvnqvvvkinnelnetslpcgatkiln
ngrklakpyfdffnysglqrsvwvialpeesvkdysvdyelcgtdalvkyevvttgehpv
ivrlldaegelvaetegkegilqvanarlwevrnaylyqivilitdgngvldeyrekigi
rtvriegtkillndrpvylkgfgkhedfpilgrgfhwgivkrdfeclkwtnancfrtshy
pyaeewyqfadeegfliidevpavgmmrstrnfvaagsgnytyffealtvpellkshiad
teemitrdknhpsviawslfnepetitdyayeyfkevfaaaetydfqsrpmtgafeknsk
pelckcyplcdficlnryygwyisggpeieeaeelfrdemdrwkakelnvpfvftefgtd
tmaglhklpsimwseeyqkeylemnfrvfdsyefvqgelawnfadfqttegimrvdgnhk
gvftrdrqpkaaavvfkdrwekknelf

    Sequence, based on observed residues (ATOM records): (download) 
    >5z18D (D:)
leyselypiqneyrmmqsldgmwkfqfdpeeigkksgwenglpapvsmpvpssfadfftd
hkerdycgdfwyetefylpaewrnkkiwlrfgsithrgtvycngmeitsheggflpvlad
istvakpgqvnqvvvkinnelnetslpcgatkilnngrklakpyfdffnysglqrsvwvi
alpeesvkdysvdyelcgtdalvkyevvttgehpvivrlldaegelvaetegkegilqva
narlwevrnaylyqivilitdgngvldeyrekigirtvriegtkillndrpvylkgfgkh
edfpilgrgfhwgivkrdfeclkwtnancfrtshypyaeewyqfadeegfliidevpavg
mmrsytyffealtvpellkshiadteemitrdknhpsviawslfnepetitdyayeyfke
vfaaaetydfqsrpmtgafeknskpelckcyplcdficlnryygwyisggpeieeaeelf
rdemdrwkakelnvpfvftefgtdtmaglhklpsimwseeyqkeylemnfrvfdsyefvq
gelawnfadfqttegimrvdgnhkgvftrdrqpkaaavvfkdrwekknelf

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >5z18E (E:)
mhhhhhhssgvdlgtenlyfqsngmleyselypiqneyrmmqsldgmwkfqfdpeeigkk
sgwenglpapvsmpvpssfadfftdhkerdycgdfwyetefylpaewrnkkiwlrfgsit
hrgtvycngmeitsheggflpvladistvakpgqvnqvvvkinnelnetslpcgatkiln
ngrklakpyfdffnysglqrsvwvialpeesvkdysvdyelcgtdalvkyevvttgehpv
ivrlldaegelvaetegkegilqvanarlwevrnaylyqivilitdgngvldeyrekigi
rtvriegtkillndrpvylkgfgkhedfpilgrgfhwgivkrdfeclkwtnancfrtshy
pyaeewyqfadeegfliidevpavgmmrstrnfvaagsgnytyffealtvpellkshiad
teemitrdknhpsviawslfnepetitdyayeyfkevfaaaetydfqsrpmtgafeknsk
pelckcyplcdficlnryygwyisggpeieeaeelfrdemdrwkakelnvpfvftefgtd
tmaglhklpsimwseeyqkeylemnfrvfdsyefvqgelawnfadfqttegimrvdgnhk
gvftrdrqpkaaavvfkdrwekknelf

    Sequence, based on observed residues (ATOM records): (download) 
    >5z18E (E:)
leyselypiqneyrmmqsldgmwkfqfdpeeigkksgwenglpapvsmpvpssfadfftd
hkerdycgdfwyetefylpaewrnkkiwlrfgsithrgtvycngmeitsheggflpvlad
istvakpgqvnqvvvkinnelnetslpcgatkilnngrklakpyfdffnysglqrsvwvi
alpeesvkdysvdyelcgtdalvkyevvttgehpvivrlldaegelvaetegkegilqva
narlwevrnaylyqivilitdgngvldeyrekigirtvriegtkillndrpvylkgfgkh
edfpilgrgfhwgivkrdfeclkwtnancfrtshypyaeewyqfadeegfliidevpavg
mmrstyffealtvpellkshiadteemitrdknhpsviawslfnepetitdyayeyfkev
faaaetydfqsrpmtgafeknskpelckcyplcdficlnryygwyisggpeieeaeelfr
demdrwkakelnvpfvftefgtdtmaglhklpsimwseeyqkeylemnfrvfdsyefvqg
elawnfadfqttegimrvdgnhkgvftrdrqpkaaavvfkdrwekk

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >5z18F (F:)
mhhhhhhssgvdlgtenlyfqsngmleyselypiqneyrmmqsldgmwkfqfdpeeigkk
sgwenglpapvsmpvpssfadfftdhkerdycgdfwyetefylpaewrnkkiwlrfgsit
hrgtvycngmeitsheggflpvladistvakpgqvnqvvvkinnelnetslpcgatkiln
ngrklakpyfdffnysglqrsvwvialpeesvkdysvdyelcgtdalvkyevvttgehpv
ivrlldaegelvaetegkegilqvanarlwevrnaylyqivilitdgngvldeyrekigi
rtvriegtkillndrpvylkgfgkhedfpilgrgfhwgivkrdfeclkwtnancfrtshy
pyaeewyqfadeegfliidevpavgmmrstrnfvaagsgnytyffealtvpellkshiad
teemitrdknhpsviawslfnepetitdyayeyfkevfaaaetydfqsrpmtgafeknsk
pelckcyplcdficlnryygwyisggpeieeaeelfrdemdrwkakelnvpfvftefgtd
tmaglhklpsimwseeyqkeylemnfrvfdsyefvqgelawnfadfqttegimrvdgnhk
gvftrdrqpkaaavvfkdrwekknelf

    Sequence, based on observed residues (ATOM records): (download) 
    >5z18F (F:)
leyselypiqneyrmmqsldgmwkfqfdpeeigkksgwenglpapvsmpvpssfadfftd
hkerdycgdfwyetefylpaewrnkkiwlrfgsithrgtvycngmeitsheggflpvlad
istvakpgqvnqvvvkinnelnetslpcgatkilnngrklakpyfdffnysglqrsvwvi
alpeesvkdysvdyelcgtdalvkyevvttgehpvivrlldaegelvaetegkegilqva
narlwevrnaylyqivilitdgngvldeyrekigirtvriegtkillndrpvylkgfgkh
edfpilgrgfhwgivkrdfeclkwtnancfrtshypyaeewyqfadeegfliidevpavg
mmrsffealtvpellkshiadteemitrdknhpsviawslfnepetitdyayeyfkevfa
aaetydfqsrpmtgafeknskpelckcyplcdficlnryygwyisggpeieeaeelfrde
mdrwkakelnvpfvftefgtdtmaglhklpsimwseeyqkeylemnfrvfdsyefvqgel
awnfadfqttegimrvdgnhkgvftrdrqpkaaavvfkdrwe